Evidence map›Paper›PMID 41767339›Full record

ArticleACG case reports journal2026

Esophageal Crohn's Disease Successfully Treated With Risankizumab.

Taylor Hallcox, Daniel Stein

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Taylor HallcoxDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID https://orcid.org/0000-0002-7289-8580
Daniel SteinDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal Crohn's disease (CD) is poorly studied despite being a significant predictor of intestinal CD progression and recurrence. Management has historically focused on steroids and acid suppression, with some success from immunosuppressants and biologics like antitumor necrosis factor-α agents. However, no specific guidelines exist for treating esophageal CD. Risankizumab, a human monoclonal antibody of interleukin-23, has shown promise in treating both induction and maintenance of remission in CD. This case series represents the first reported use of risankizumab in esophageal CD. Despite the absence of guidelines for esophageal CD management, these cases suggest that risankizumab may offer a valuable treatment option and should be strongly considered for managing esophageal CD.

Indexed as

esophageal Crohn's diseaseinterleukin-23 inhibitorrefractory Crohn's diseaserisankizumab

Identifiers

PMID41767339
PMCPMC12947984

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.