Evidence map›Paper›PMID 41767304›Full record

ReviewFrontiers in genetics2026

Recent advances in the detection technologies for balanced chromosomal rearrangements.

Meng Gao, Jun Ren, Shanling Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meng GaoDepartment of Medical Genetics, Center for Prenatal Diagnosis, West China Second University Hospital, Sichuan University, Chengdu, China.
Jun Ren *Department of Medical Genetics, Center for Prenatal Diagnosis, West China Second University Hospital, Sichuan University, Chengdu, China.
Shanling Liu *Department of Medical Genetics, Center for Prenatal Diagnosis, West China Second University Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balanced chromosomal rearrangements (BCRs) refer to a type of chromosomal structural variations without chromosomal gains or losses. BCR carriers may experience fertility issues, including a higher risk of infertility, recurrent miscarriages, or having offspring with chromosomal abnormalities. Since there are no apparent gains or losses of genetic materials in BCR carriers, their detection has long been a focal and challenging issue in the field of chromosomal structural variation analysis. Karyotyping cannot detect submicroscopic rearrangements because of restricted resolution and the application of fluorescence

Indexed as

balanced chromosomal rearrangementsclinical laboratory techniquesgenome sequencingmolecular genetic testingoptical genome mapping

Identifiers

PMID41767304
PMCPMC12945333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.