Pannexin 1a regulates visual system development and ocular integrity in zebrafish.

Shiva Sabour, Sarah Houshangi-Tabrizi, Georg S O Zoidl, Georg R Zoidl, Nima Tabatabaei

Abstract read

In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shiva SabourDepartment of Mechanical Engineering, York University, Toronto, ON, Canada.

Sarah Houshangi-TabriziDepartment of Biology, York University, Toronto, ON, Canada.

Georg S O ZoidlDepartment of Biology, York University, Toronto, ON, Canada.

Georg R ZoidlDepartment of Biology, York University, Toronto, ON, Canada.

Nima TabatabaeiDepartment of Mechanical Engineering, York University, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pannexin 1a (Panx1a), a large-pore ATP release channel broadly expressed in the vertebrate eye, has an unclear role in ocular development. Using a zebrafish Panx1a knockout, we observed progressive ocular phenotypes, including impaired visuomotor behavior, axial myopia, cataract-like lens abnormalities, lens defects, and retinal thinning. Optokinetic response (OKR) assays revealed markedly reduced responsiveness in Panx1a

Indexed as

Developmental neuroscienceMolecular neuroscienceSensory neuroscience

Identifiers

PMID41767272

DOI10.1016/j.isci.2026.114925

PMCPMC12937171

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.