Evidence map›Paper›PMID 41767104›Full record

ArticleThe application of clinical genetics2026

Ha Minh Nguyen, Duong Hoang Huy Le, Tham Thi Hong Ho, Phuc Doan Huynh Anh Nguyen, Thinh Hung Nguyen, Van Nguyen Thanh Phan, Tuan Huu Ngoc Nguyen

Abstract read
In one paragraph

Article in The application of clinical genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ha Minh NguyenBiomedical Research and Diagnostics Center, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.ORCID 0000-0001-5125-1828
Duong Hoang Huy LeBiomedical Research and Diagnostics Center, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.ORCID 0009-0007-5524-4626
Tham Thi Hong HoBiomedical Research and Diagnostics Center, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.ORCID 0009-0007-6888-9685
Phuc Doan Huynh Anh NguyenBiomedical Research and Diagnostics Center, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
Thinh Hung NguyenBiomedical Research and Diagnostics Center, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.ORCID 0009-0004-3641-2821
Van Nguyen Thanh PhanFaculty of Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
Tuan Huu Ngoc NguyenBiomedical Research and Diagnostics Center, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.ORCID 0009-0009-0635-7979

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic obstructive pulmonary disease (COPD) poses a significant health burden in Vietnam. The Methods: A cross-sectional study recruited 320 healthy controls and 266 stable COPD patients (per GOLD 2023 criteria) from October 2024 to August 2025. Clinical data were collected from medical records and direct interrogation. Genotyping was performed using PCR-RFLP. The dataset used for sensitivity analyses (2,660 observations) was created through multiple imputations to address missing clinical data. Associations of the rs1800629 with disease susceptibility and selected clinical management parameters were analyzed using Chi-square/Fisher's exact tests, multivariable logistic regression, and sensitivity analysis. Results: The A allele frequencies were 8.83% (COPD), 6.88% (controls), and 7.77% overall ( Conclusion: Our findings suggest a possible protective recessive association of the

Indexed as

COPDpolymorphismrs1800629TNF-αVietnam

Identifiers

PMID41767104
PMCPMC12948766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.