Trial reportFrontiers in neurology
Association of the neutrophil percentage-to-albumin ratio after endovascular treatment and 3-month clinical outcomes.
Trial report in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05092139 (enDovascular trEatmenT for acutE isChemic sTroke in China), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
enDovascular trEatmenT for acutE isChemic sTroke in China (DETECT2-China): a Prospective, National, Multi-center, Registry Study
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim: Neutrophil percentage-to-albumin ratio (NPAR) is associated with clinical outcomes in malignancy, cardiovascular disease, and stroke. This study aimed to evaluate whether NPAR levels are associated with clinical outcomes in patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO) who underwent endovascular treatment (EVT). Methods: From a prospective cohort, we consecutively enrolled patients with anterior circulation LVO-AIS who underwent EVT and had available admission and 48-h post-EVT NPAR data. Three-month clinical outcome was assessed using the modified Rankin Scale (mRS). Poor functional outcome was defined as functional dependence or death (mRS 3-6). Multivariable logistic regression analyses were performed to explore the relationship between NPAR levels and clinical outcomes. Results: A total of 121 eligible patients were included in the final analysis. Multivariable logistic regression models showed that a higher 48-h NPAR level (Model 1: adjusted OR = 15.09, 95% CI 3.72-61.22, Conclusion: Higher 48-h follow-up NPAR levels and increases in NPAR from admission to 48 h were independent predictors of poor 3-month functional outcomes in patients with large vessel occlusion treated with endovascular therapy. Clinical trial registration: https://www.clinicaltrials.gov, identifier (NCT05092139).
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