Evidence map›Paper›PMID 41766793›Full record

ArticleFindings of ACL. ACL2024

Knowledge-Infused Prompting: Assessing and Advancing Clinical Text Data Generation with Large Language Models.

Ran Xu, Hejie Cui, Yue Yu, Xuan Kan, Wenqi Shi, Yuchen Zhuang, May D Wang, Wei Jin, Joyce C Ho, Carl Yang

Abstract read
In one paragraph

Article in Findings of ACL. ACL, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Synth-SBDH: A Synthetic Dataset of Social and Behavioral Determinants of Health for Clinical Text.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2025
    Article
  6. A Survey on Unifying Large Language Models and Knowledge Graphs for Biomedicine and Healthcare.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ran XuEmory University.
Hejie CuiEmory University.
Yue YuGeorgia Institute of Technology.
Xuan KanEmory University.
Wenqi ShiGeorgia Institute of Technology.
Yuchen ZhuangGeorgia Institute of Technology.
May D WangGeorgia Institute of Technology.
Wei JinEmory University.
Joyce C HoEmory University.
Carl YangEmory University.

Funding

Understanding Diabetes Heterogeneity via Mining Multimodality Interconnected DataK25DK135913 · NIDDK · EMORY UNIVERSITY · PI Ji Carl Yang · 2023 to 2026
$687k
NIDDK NIH HHS K25 DK135913
6 · The paper itself

Abstract

Clinical natural language processing faces challenges like complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet, their direct deployment can lead to privacy issues and are constrained by resources. To address this challenge, we delve into synthetic clinical text generation with LLMs for clinical NLP tasks. We propose an innovative, resource-efficient approach, ClinGen, which infuses knowledge into the process. Our model involves clinical knowledge extraction and context-informed LLM prompting. Both clinical topics and writing styles are drawn from external domain-specific knowledge graphs and LLMs to guide data generation. Our extensive empirical study across 8 clinical NLP tasks and 18 datasets reveals that ClinGen consistently enhances performance across various tasks by 7.7%-8.7% on average, effectively aligning the distribution of real datasets and enriching the diversity of generated training instances. Our code is available at https://github.com/ritaranx/ClinGen.

Identifiers

PMID41766793
PMCPMC12949634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.