Evidence map›Paper›PMID 41766707›Full record

ArticleCJC open2026

Residual Mitral Regurgitation After Transcatheter Edge-to-Edge Repair Worsens Survival in Patients with Renal Dysfunction.

Dennis Rottländer, Jörg Hausleiter, Thomas Schmitz, Alexander Bufe, Melchior Seyfarth, Harald Beucher, Taoufik Ouarrak, Steffen Schneider, Peter Boekstegers, MITRA-PRO investigators

Abstract read
In one paragraph

Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dennis RottländerDepartment of Cardiology, Faculty of Health, Witten/Herdecke University, Witten, Germany.
Jörg HausleiterDepartment of Cardiology, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.
Thomas SchmitzDepartment of Cardiology, Elisabeth Krankenhaus, Essen, Germany.
Alexander BufeDepartment of Cardiology, Faculty of Health, Witten/Herdecke University, Witten, Germany.
Melchior SeyfarthDepartment of Cardiology, Faculty of Health, Witten/Herdecke University, Witten, Germany.
Harald BeucherDepartment of Cardiology, Helios Klinikum Siegburg, Siegburg, Germany.
Taoufik OuarrakInstitut für Herz-Infarkt Forschung, Ludwigshafen, Germany.
Steffen SchneiderInstitut für Herz-Infarkt Forschung, Ludwigshafen, Germany.
Peter BoekstegersDepartment of Cardiology, Faculty of Health, Witten/Herdecke University, Witten, Germany.
MITRA-PRO investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic kidney disease (CKD) and postprocedural acute kidney injury (AKI) are predictors of survival after mitral transcatheter edge-to-edge repair (TEER). This study aimed to assess the impact of residual mitral regurgitation (MR) on 3-year mortality in patients with vs without CKD or AKI. Methods: Patients from the prospective, multicentre MITRAClip PROgnosis (MITRA-PRO) registry (n = 1491) were stratified by baseline estimated glomerular filtration rate (eGFR), into 3 groups: > 50, 30-50, and < 30 mL/min per 1.73 m Results: Patients with eGFR < 30 had significantly higher 3-year mortality (55.4%) compared to those with eGFR 30-50 (40.8%) and eGFR > 50 (27.7%, Conclusions: Residual MR following TEER is a strong predictor of long-term mortality, particularly in patients with CKD. Minimizing residual MR may reduce postprocedural AKI and improve survival outcomes in patients with CKD. Clinical Trial Registration: DRKS00012288.

Indexed as

acute kidney injuryedge-to-edge repairmitral regurgitationrenal failureresidual regurgitationtranscatheter mitral valve repair

Identifiers

PMID41766707
PMCPMC12946798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.