Evidence map›Paper›PMID 41766703›Full record

ArticleCJC open2026

Left Atrial Intracardiac Echocardiography to Assist Zero Fluoroscopy Pulse Field Atrial Fibrillation Ablation-A Beginner's Guide.

Intisar Ahmed, Carolina Guerrero-Pando, Nathan Denham, Mahbod Rahimi, Erica Muscat, Takahiro Hayashi, Carlo Duc-Malagisi, Ahmad Samoud, Vijay S Chauhan, Andrew C T Ha and 1 more

Abstract read
In one paragraph

Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Intisar AhmedPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Carolina Guerrero-PandoPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Nathan DenhamPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Mahbod RahimiPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Erica MuscatPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Takahiro HayashiPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Carlo Duc-MalagisiAbbott Medical Canada, Mississauga, Ontario, Canada.
Ahmad SamoudMedtronic, Cardiac Ablation Solutions Division, Toronto, Ontario, Canada.
Vijay S ChauhanPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Andrew C T HaPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Abhishek BhaskaranPeter Munk Cardiac Centre, Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulsed-field ablation (PFA) has emerged as a novel energy source for the management of atrial fibrillation (AF), offering improved tissue selectivity and a better safety profile. Although fluoroscopy has traditionally guided catheter positioning, the integration of intracardiac echocardiography (ICE), particularly from a left atrial (LA) vantage point, presents an opportunity for real-time visualization and enhanced procedural precision. In this paper, we describe a workflow for LA-ICE-guided PFA, without using fluoroscopy, and present preliminary data from our centre. Methods: All patients who underwent PFA for AF since December 2024 were screened, and those who underwent LA-ICE-guided ablation were included in the study. After patients provided informed consent, procedures were performed under general anesthesia with muscle relaxants to minimize stimulation of extracardiac muscles. Results: LA-ICE-guided PFA was performed in 100 consecutive patients with paroxysmal (73%) and persistent (27%) AF at a single centre. Zero-fluoroscopy (ZF) ablation was successfully performed in 28 patients, without any major complications. The challenges encountered during ZF ablation included enlarged atria, thick interatrial septum, venous tortuosity, aortic root aneurysm, and pacemaker leads. Visualizing the FlexCath sheath while crossing the interatrial septum and confirming its position in the left atrium immediately after crossing does require some effort, especially in a dilated left atrium. Conclusions: LA-ICE facilitates ZF-PFA for AF by offering superior visualization of the LA anatomy, continuous monitoring of catheter orientation, precise catheter positioning, and maintenance of catheter-tissue contact.

Indexed as

ablationAtrial fibrillationintracardiac echocardiogramLeft atrialpulsed-field

Identifiers

PMID41766703
PMCPMC12946806

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.