ArticleCJC open2026
Infective Endocarditis in Patients with Mitral Annular Calcification: Clinical and Echocardiographic Presentation, Management, and Outcomes.
Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Valve-Specific Anatomy and Structural Determinants of Susceptibility to Infective Endocarditis: A Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mitral annular calcification (MAC) poses unique challenges in infective endocarditis (IE). This study aimed to characterize echocardiographic features of IE involving MAC and assess its management and outcomes. Methods: We reviewed cases discussed during our IE multidisciplinary meetings, 2021-2024. Clinical data, imaging findings, and outcomes were collected through chart review. Results: Among 741 patients evaluated, 51 patients (7%; aged 73 ± 11 years; 45% female) had possible or definite IE and moderate-severe MAC. IE involved the mitral valve in 24 patients (47%). Mitral IE was more frequent in women (63% vs 30%, Conclusions: In patients with IE and MAC, the mitral valve was often primarily affected, showing large, mobile vegetations with a "rocking" motion. Despite frequent surgical indications, few underwent surgery, highlighting the need for improved management in this high-risk group.
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Registered trials
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