ArticleEpidemiology and infection2026
Antimicrobial prescribing patterns at a South African tertiary referral hospital: Insights from three global point prevalence surveys.
Article in Epidemiology and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Antimicrobial resistance (AMR) is a pressing global health challenge, with sub-Saharan Africa experiencing the highest burden of AMR-related deaths. Inappropriate prescribing and rising antibiotic consumption drive AMR, while limited local data hampers antimicrobial stewardship efforts. This study analysed Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) data from Tygerberg Hospital to identify antimicrobial use trends and inform stewardship priorities. Standard Global-PPS methodology was employed at three distinct time points. All inpatients prescribed at least one antimicrobial on the day of each survey were included in the analysis. Among 3,524 hospitalized patients, 25.9% (911/3,524) received antimicrobial therapy. Overall antimicrobial use decreased significantly (
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