Evidence map›Paper›PMID 41766302›Full record

ArticleJournal of clinical psychology2026

The Burden of Disease of Treatment-Seeking Patients With a Cluster-C Personality Disorder in the Netherlands; Quality of Life, Functioning, and Societal Costs.

Iuno Z Groot, Arnoud Arntz, Carlijn J M Wibbelink, Bas Verhoeven, Nathan R Bachrach, Silvia M A A Evers

Abstract read
In one paragraph

Article in Journal of clinical psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Iuno Z GrootDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-5744-4567
Arnoud ArntzDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands.
Carlijn J M WibbelinkDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-6002-6892
Bas VerhoevenDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands.
Nathan R BachrachDepartment of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands.ORCID 0000-0002-0746-2692
Silvia M A A EversDepartment of Health Services Research, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, the Netherlands.

Funding

ZonMw 636310019
6 · The paper itself

Abstract

Cluster-C personality disorders (PDs) are common in the general population but often overlooked in scientific research and clinical practice. An important step to increase awareness for timely diagnosis and treatment of cluster-C PDs is to investigate the burden of disease in terms of quality of life (QoL), daily functioning and the associated costs to society. In addition, a comparison between these patients and a control group can give insight into (1) the actual societal costs that are associated to cluster-C PD problems and (2) potential societal savings to be made from therapeutic interventions. This study included a total of 375 treatment seeking individuals from 10 mental health sites for outpatient treatment in the Netherlands and 104 individuals without severe mental health issues from the general population. Both QoL (EQ-5D-5L and the MHQoL-7D) and general functioning (WHODAS) were assessed as well as a comprehensive cost-interview to measure relevant costs considering a societal perspective. Results indicate that individuals with a cluster-C PD have severely impaired QoL and functioning compared to the control group. The annual costs associated with cluster-C PD were estimated ranging from €27,355 to €60,454 per patient per year depending on the valuation method used. These costs equate 2.8-4.2 times more than those of control group. Looking at the subgroup in cluster-C PD, no differences in QoL, functioning or societal costs were found between individuals with avoidant, dependent and obsessive-compulsive PD. Overall, the findings advocate for more financial resources to study, prevent and treat cluster-C PDs.

Indexed as

Compulsive Personality DisorderCost of IllnessHealth Care CostsPersonality DisordersQuality of LifeAdultFemaleHumansMaleMiddle AgedNetherlandsYoung Adultburden of diseasecluster‐C personality disorderscost‐off‐illnessquality of lifesocietal costs

Identifiers

PMID41766302
PMCPMC13064880

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.