Evidence map›Paper›PMID 41766292›Full record

ReviewCurrent opinion in HIV and AIDS2026

The HIV reservoir landscape in elite controllers.

Cristina Moral-Turón, María Antequera-Martínez, Ezequiel Ruiz-Mateos

Abstract readReview
In one paragraph

Review in Current opinion in HIV and AIDS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cristina Moral-TurónInstitute of Biomedicine of Seville, IBiS/Virgen Del Rocío University Hospital/CSIC/University of Seville, Clinical Unit of Infectious Diseases, Microbiology and Parasitology, Seville, Spain.
María Antequera-Martínez
Ezequiel Ruiz-Mateos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewIn this review, we intend to define the main characteristics of the elite controller reservoir, exploring into its heterogeneity, which goes hand in hand with the different progression phenotypes within elite controllers. RECENT

findingsShow that the viral reservoir measured by high-resolution techniques in elite controllers is heterogeneous, exhibiting distinct characteristics in elite controllers who ultimately lose control compared to those with persistent viral remission. Among the latter, we find exceptional individuals with a reservoir consistent with a phenomenon of "block and lock," and even with a potential sterilizing cure. SUMMARY: The HIV-1 reservoir in elite controllers is heterogeneous; discriminating the distinct characteristics of reservoir profiles in elite controllers can provide important clues about how to achieve an HIV cure.

Indexed as

Elite ControllersHIV-1HIV InfectionsHumansViral Loadelite controllersHIV cureintact and defective provirusesreservoir

Identifiers

PMID41766292
PMCPMC13048317

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.