Evidence map›Paper›PMID 41766260›Full record

Observational studyObesity (Silver Spring, Md.)2026

Twenty-Four Month Outcomes From a Real-World Telehealth Obesity Treatment Clinic Using Obesity Medications.

Kathleen R Ruddiman, Young-Rock Hong, Jamy Ard, Rebecca Jones, Adam Medcalf, Gary D Foster, Jamil Alkhaddo, Michelle Cardel

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathleen R RuddimanDepartment of Surgery, Bariatric and Weight Management Section, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0009-0005-5721-1874
Young-Rock HongDepartment of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Jamy ArdDepartment of Surgery, Bariatric and Weight Management Section, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Rebecca JonesWW International, Inc., New York, New York, USA.
Adam MedcalfWW International, Inc., New York, New York, USA.
Gary D FosterCenter for Weight and Eating Disorders, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3960-0332
Jamil AlkhaddoWW International, Inc., New York, New York, USA.ORCID https://orcid.org/0000-0001-9949-5119
Michelle CardelWW International, Inc., New York, New York, USA.

Funding

WW International, Inc.
6 · The paper itself

Abstract

objectiveAntiobesity medications (AOMs) are indicated for long-term use; however, evidence of their real-world long-term efficacy is limited. This study describes clinical outcomes from 18- and 24-month use of AOMs in a telemedicine weight management clinic.

methodsThis retrospective observational study analyzed data from adult participants who utilized AOMs at a telemedicine weight management clinic between January 2022 and December 2024. Weight change analyses were conducted for those maintaining AOM use for ≥ 18 months (n = 11,675) and ≥ 24 months (n = 4317). Weight outcomes were assessed across all AOMs and stratified based on classification of AOMs utilized.

resultsAcross all AOMs, average total body weight reduction of -18.53% (95% CI: -18.74%, -18.32%) was observed at 18 months and -20.27% (95% CI: -20.63%, -19.92%) seen at 24 months. For those taking long-acting AOMs, outcomes trended toward greater weight loss in comparison with participants using oral AOMs.

conclusionsThis real-world analysis found 18- and 24-month weight losses comparable to those demonstrated in clinical trials, supporting the long-term efficacy of AOMs provided by a telemedicine weight management clinic. Continued weight loss was demonstrated between 18 and 24 months, suggesting sustained engagement with AOMs and a telemedicine weight management clinic support continued weight loss in the long term.

Indexed as

Anti-Obesity AgentsObesityAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTelemedicineTreatment OutcomeWeight LossAnti-Obesity AgentsAOMobesity medicationreal‐world outcomestelemedicine clinic

Identifiers

PMID41766260
PMCPMC13250737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.