ArticleIndian journal of pharmacology2026
Therapy in diabetic dyslipidemia.
Article in Indian journal of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionDiabetics have an increased cardiovascular risk. This risk gets exaggerated by lipid abnormalities additionally. Diabetics have an increased propensity to develop dyslipidemia. Diabetic dyslipidemia is a cluster of lipoprotein abnormalities characterized by increased triglyceride and low-density lipoprotein levels, decreased high-density lipoprotein levels. MATERIALS AND
methodsFrom the pilot study, a potent dose of saroglitazar and gemfibrozil was selected for this study. In this study, the experimental rats were divided into five groups of six animals in each group.
resultsCombination therapy shows a decrease in lipid profile, atherogenic index, histopathological studies of different organs, and insulin levels compared to individual drugs and shows better therapeutic efficacy.
conclusionHence, the combination of saroglitazar and gemfibrozil has shown a good safety profile and may represent a novel therapeutic agent that will fulfill the unmet needs in T2DM and diabetic dyslipidemia.
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