Evidence map›Paper›PMID 41766144›Full record

Trial reportZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2026

[Application and comparative study of critical care ultrasound and noninvasive cardiac output monitoring in fluid resuscitation of neonatal septic shock: a randomized controlled trial].

Bing-Hui Li, Zhen-Yu Liang, Ling-Ling Chen, Zhuo-Nan Liu, De-Bo Xu, Qiong Meng

Abstract readRandomized Controlled TrialComparative StudyEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bing-Hui LiDepartment of Pediatrics, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 510220, China.
Zhen-Yu LiangDepartment of Pediatrics, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 510220, China.
Ling-Ling ChenDepartment of Pediatrics, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 510220, China.
Zhuo-Nan LiuDepartment of Pediatrics, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 510220, China.
De-Bo XuDepartment of Pediatrics, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 510220, China.
Qiong MengDepartment of Pediatrics, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 510220, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the effectiveness of critical care ultrasound and noninvasive cardiac output monitoring (NICOM) in guiding fluid resuscitation in neonatal septic shock by dynamically assessing responsiveness to fluid therapy and comparing treatment outcomes and clinical applicability.

methodsA total of 51 neonates were enrolled. Before initiation of fluid resuscitation, patients were randomly assigned to receive fluid resuscitation guided by critical care ultrasound or by NICOM. Differences in 14-day mortality and other clinical outcomes after the onset of septic shock were compared between the two groups.

resultsNo significant difference was found in 14-day mortality between the critical care ultrasound group and the NICOM group (

conclusionsIn neonates with septic shock, the risks of acute kidney injury and intracranial hemorrhage within 72 hours are lower under NICOM guidance than with critical care ultrasound, whereas fluid resuscitation guided by critical care ultrasound reduces the risk of pulmonary edema. Both critical care ultrasound and NICOM are simple, low-cost, noninvasive tools that can assist in guiding fluid resuscitation in neonatal septic shock.

Indexed as

Cardiac OutputCritical CareFluid TherapyResuscitationShock, SepticFemaleHumansInfant, NewbornMaleMonitoring, PhysiologicUltrasonographyCritical care ultrasoundFluid resuscitationNeonateNoninvasive cardiac output monitoringSeptic shock

Identifiers

PMID41766144
PMCPMC12950960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.