Evidence map›Paper›PMID 41766130›Full record

ArticlePediatric emergency care2026

Physician-Reported Diagnostic Uncertainty Among Children Discharged From the Pediatric Emergency Department With Acute Respiratory Illness.

Alexandra T Geanacopoulos, Carolyn Drescher, Joseph Kanaan, Mark I Neuman, Alon Peltz, Mei-Sing Ong, Christina L Cifra, Kathleen E Walsh

Abstract read
In one paragraph

Article in Pediatric emergency care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra T GeanacopoulosDivision of Emergency Medicine.ORCID 0000-0002-8928-5588
Carolyn DrescherDivision of Emergency Medicine.
Joseph KanaanDivision of Emergency Medicine.
Mark I NeumanDivision of Emergency Medicine.
Alon PeltzDepartment of Pediatrics, Boston Children's Hospital.
Mei-Sing OngDepartment of Pediatrics, Boston Children's Hospital.
Christina L CifraDivision of Medical Critical Care, Boston Children's Hospital, Boston, MA.
Kathleen E WalshDepartment of Pediatrics, Boston Children's Hospital.

Funding

RESEARCH TRAINING IN PEDIATRIC EMERGENCY MEDICINET32HD040128 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI Kenneth D. Mandl · 2001 to 2026
$5.0M
Sociomarkers to Predict Asthma Control and Emergency Room Visits (SPACER)K23HL155425 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI PELTZ, ALON · 2021 to 2025
$847k
AHRQ HHS T32 HS000063NHLBI NIH HHS K23 HL155425NICHD NIH HHS T32 HD040128
6 · The paper itself

Abstract

objectivesDiagnostic uncertainty is an important, yet understudied, driver of patient safety within pediatric emergency medicine. Understanding how uncertainty is experienced and communicated may reveal opportunities to optimize patient safety. This study aims to determine the frequency of physician-reported uncertainty at emergency department (ED) discharge for pediatric acute respiratory illness and to describe strategies and challenges in communicating uncertainty to caregivers.

methodsThis was a cross-sectional study of children (<18 y) discharged with acute respiratory illness from a tertiary care pediatric ED (April to May 2025). For each patient, the discharging attending physician completed a survey assessing diagnostic uncertainty (6-point Likert scale, dichotomized for analysis), and whether and how this was communicated to caregivers. Physicians indicated their general overall comfort communicating uncertainty. Wilson CIs were calculated around the prevalence of visits with uncertainty.

resultsAmong 220 patients with acute respiratory illness, 68 (31%, 95% 25 to 37%) were discharged with diagnostic uncertainty. Uncertainty was communicated to 61 caregivers (90%) in the following ways: using terms such as "maybe," "probably," or "likely" (74%), provision of return precautions (59%), discussion of the differential diagnosis (56%), and discussion of diagnoses excluded (27%). Many (45% of 60 physicians surveyed) reported communication challenges, citing perceived caregiver expectations, anxiety, and risk communication concerns.

conclusionsDiagnostic uncertainty occurred in nearly one-third of ED discharges for pediatric acute respiratory illness. Communication approaches varied, and several challenges were noted. Future research engaging clinicians and families is needed to address these challenges and develop optimal methods of family-centered communication of uncertainty.

Indexed as

Emergency Service, HospitalPatient DischargePhysiciansRespiratory Tract DiseasesAcute DiseaseAdolescentChildChild, PreschoolCommunicationCross-Sectional StudiesDiagnosis, DifferentialEmergency Room VisitsFemaleHumansInfantMaleacute respiratory illnesscommunicationdiagnostic uncertaintypediatric emergency care

Identifiers

PMID41766130
PMCPMC13671376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.