Evidence map›Paper›PMID 41765887›Full record

ArticleCardiovascular ultrasound2026

Association of left atrial volume and function parameters with cardiovascular outcomes following kidney transplantation.

Ava R DeLonais-Parker, Spencer H Hobbs, Taylor R Coffman, Michael F Kanan, Yanqing Lyu, Elsa J Treiber, Rushda F Mansuri, Barbara C Okeke, Krista L Lentine, Mina M Benjamin

Abstract read
In one paragraph

Article in Cardiovascular ultrasound, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ava R DeLonais-ParkerSaint Louis University School of Medicine, Saint Louis, MO, USA.
Spencer H HobbsSaint Louis University School of Medicine, Saint Louis, MO, USA.
Taylor R CoffmanSaint Louis University School of Medicine, Saint Louis, MO, USA.
Michael F KananSaint Louis University School of Medicine, Saint Louis, MO, USA.
Yanqing LyuSaint Louis University School of Medicine, Saint Louis, MO, USA.
Elsa J TreiberSaint Louis University School of Medicine, Saint Louis, MO, USA.
Rushda F MansuriDepartment of Epidemiology and Biostatistics, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO, USA.
Barbara C OkekeInternal Medicine Department, Saint Louis University Hospital, Saint Louis, MO, USA.
Krista L LentineDivision of Nephrology, Saint Louis University Hospital, Saint Louis, MO, USA.
Mina M BenjaminDivision of Cardiology, Division of Cardiovascular Medicine, SSM-Saint Louis University Hospital, 1201 S Grand Blvd.,, Saint Louis, MO, 63104, USA. mina.mehanni@health.slu.edu.ORCID http://orcid.org/0000-0001-9076-2321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLeft atrial (LA) volume and strain parameters have been associated with cardiovascular outcomes in several cardiac pathologies, yet their role in predicting major adverse cardiovascular events (MACE) in kidney transplant (KT) recipients has not been explored.

methodsWe retrospectively reviewed the records of adult KT recipients from our institution (2015-2024). We utilized baseline echocardiograms routinely acquired during KT workup to measure LA volumetrics and strain. MACE was the study's primary endpoint, defined as cardiovascular death, nonfatal myocardial infarction, stroke, major arrhythmias or heart failure hospitalization. Logistic regression, Kaplan-Meier and Cox proportional hazards regression were performed to evaluate the association between LA parameters and MACE.

resultsOf 518 patients who underwent kidney transplant, 377 were in sinus rhythm with an acceptable quality echocardiogram (male, 56.7%; mean age 53.7 ± 13.1 years). Over a median follow up duration of 5.3 ± 2.3 years from KT, 82 patients reached the study endpoint. Kaplan-Meier analysis showed significantly lower MACE-free survival in patients with abnormal LA strain. After adjusting for confounding variables in the Cox Proportional Hazards model, of all LA parameters, lower LAScd (HR 0.94, 95% CI 0.89-0.98, p = 0.003), and LASr (HR 0.97, 95% CI 0.94-0.995, p = 0.02) were independently associated with MACE.

conclusionIn this retrospective single center study, LA strain parameters particularly LASr and LAScd were independently associated with MACE after KT. LA strain might have a role in risk stratification in this population.

Indexed as

Atrial Function, LeftCardiovascular DiseasesEchocardiographyHeart AtriaKidney TransplantationPostoperative ComplicationsFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesRisk FactorsEchocardiographyKidney transplantLeft atrial strainMajor adverse cardiovascular events

Identifiers

PMID41765887
PMCPMC12951988

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