ArticleInternational journal of dermatology2026
The Impact of Steroid Use on Scabies Treatment: An Evaluation of Clinical Severity, Parasite Burden, and the Validity of a Novel Scoring System.
Article in International journal of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Steroid-Modified Scabies: Quantifying a Clinically Recognized but Understudied Problem.International journal of dermatology · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCorticosteroids are frequently used to relieve pruritus or eczematization in scabies, but empirical or prolonged use before diagnosis may modify the disease course.
objectivesThis study aimed to examine the impact of corticosteroid exposure (misdiagnosis-related or adjunctive) on clinical severity, mite burden, and healing time, and to assess the initial measurement properties of a novel composite scoring system for standardized severity assessment.
methodsIn this cross-sectional analytical study, 180 adults (18-50 years) with dermoscopically confirmed scabies were classified into three groups: misdiagnosed (steroid-only), standard therapy + steroid, and standard therapy. Severity was assessed using a 0-9 composite score integrating pruritus (NRS), mite index, and body surface area involvement (BSA). Internal consistency (Cronbach's α) and inter-rater reliability (ICC) were evaluated.
resultsBoth steroid-exposed groups showed significantly higher severity scores (all p < 0.001), longer disease duration (median 8 weeks vs. 3 weeks), and delayed healing compared with standard therapy. Steroid duration correlated with mite index, BSA, and total score (all p ≤ 0.005). The scale showed borderline-to-acceptable internal consistency; ICC was good for NRS (0.79) and fair-to-moderate for the total score (0.45).
conclusionPrior or concurrent corticosteroid exposure increases disease severity and delays recovery in scabies, likely by suppressing local immune responses. The proposed Scabies Severity Scale is a practical, preliminary tool for standardized severity assessment, pending external validation.
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