Evidence map›Paper›PMID 41764968›Full record

ArticleJournal of biomechanics2026

Effects of infraglottal implantation on voice production in type I thyroplasty: a computational study.

Weili Jiang, Charles Farbos de Luzan, Liran Oren, Ephraim Gutmark, Xudong Zheng, Qian Xue

Abstract read
In one paragraph

Article in Journal of biomechanics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weili JiangMechanical Engineering Department, Rochester Institute of Technology, Rochester, NY 14623, USA. Electronic address: wxjeme@rit.edu.
Charles Farbos de LuzanDepartment of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, OH 45267, USA. Electronic address: farboscs@ucmail.uc.edu.
Liran OrenDepartment of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, OH 45267, USA. Electronic address: orenl@ucmail.uc.edu.
Ephraim GutmarkDepartment of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, OH 45267, USA. Electronic address: gutmarej@ucmail.uc.edu.
Xudong ZhengMechanical Engineering Department, Rochester Institute of Technology, Rochester, NY 14623, USA. Electronic address: xxzeme@rit.edu.
Qian XueMechanical Engineering Department, Rochester Institute of Technology, Rochester, NY 14623, USA. Electronic address: qxxeme@rit.edu.

Funding

The Relationships Between Vortices, Acoustics, and Vibration in Vocal Fold AsymmetriesR01DC009435 · NIDCD · UNIVERSITY OF CINCINNATI · PI OREN, LIRAN · 2009 to 2025
$8.5M
NIDCD NIH HHS R01 DC009435NSF 2137603NSF 2138259NSF 2138286NSF 2138296NSF 2138307
6 · The paper itself

Abstract

Type I thyroplasty (TT1) is one of the primary phonosurgical interventions for unilateral vocal fold paralysis. This study investigated the effects of infraglottal implant placement in TT1 on voice production using numerical simulations. The laryngeal and implant geometries were reconstructed from computed tomography scan of a canine larynx with a hand-carved Silastic implant. Fluid-structure interaction simulations, coupling the continuum finite element vocal fold and implant models with a one-dimensional Bernoulli-based glottal flow model, were conducted to evaluate vocal fold vibration across a range of implant stiffnesses, insertion depths, and vertical positions. Effects of implant parameters on pre-phonatory shape and stiffness, glottal flow and vocal fold dynamics and acoustic outcome have been analyzed. The results revealed that infraglottal implants can enhance both sound pressure level (SPL) and vocal efficiency (VE) when the insertion depth exceeds a certain threshold. The observed enhancement in SPL and VE was attributed to an increased vertical stiffness gradient in the vocal folds induced by the inferior implant, which leads to greater force asymmetry between vocal folds opening and closing, thereby promoting more effective energy transfer from the glottal airflow to the vocal folds. The result is larger vocal fold vibrations, which leads to a larger SPL and may also contribute to the improved VE. The current simulation is based on the simulation of one single canine larynx. Future studies incorporating more subjects would help to generalize the current findings.

Indexed as

LaryngoplastyModels, BiologicalVocal Cord ParalysisVocal CordsVoiceAnimalsComputer SimulationDogsFinite Element AnalysisLarynxPhonationProstheses and ImplantsVibrationFluid–structure interactiontype IthyroplastyVirtual surgeryVocal fold biomechanicsVoice production

Identifiers

PMID41764968
PMCPMC13289833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.