Evidence map›Paper›PMID 41764875›Full record

ArticlePatient education and counseling2026

Navigating prognostic uncertainty with H.O.P.E.: Caring for elderly patients with chronic kidney disease.

Nataly R Espinoza Suarez, Susan Curtis, Iris Hargraves, Kasey Boehmer, Margaret d'Uscio, Brigid Amberg, Erica J Sutton, Annika Beck, Annie LeBlanc, Allyson Hart and 2 more

Abstract read
In one paragraph

Article in Patient education and counseling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nataly R Espinoza SuarezVITAM Research Center on Sustainable Health, Quebec Integrated University Health and Social Services Center, Québec, Canada; Knowledge Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA.
Susan CurtisBiomedical Ethics Research Program, Mayo Clinic, Rochester, MN, USA.
Iris HargravesKnowledge Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA.
Kasey BoehmerKnowledge Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA.
Margaret d'UscioDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Brigid AmbergDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Erica J SuttonBiomedical Ethics Research Program, Mayo Clinic, Rochester, MN, USA.
Annika BeckBiomedical Ethics Research Program, Mayo Clinic, Rochester, MN, USA.
Annie LeBlancVITAM Research Center on Sustainable Health, Quebec Integrated University Health and Social Services Center, Québec, Canada; Faculty of Medicine, Laval University, Quebec, Canada.
Allyson HartDivision of Nephrology, Department of Medicine, Hennepin Healthcare, Minneapolis, MN, USA; University of Minnesota Medical School, Minneapolis, MN, USA.
Jon TilburtBiomedical Ethics Research Program, Mayo Clinic, Rochester, MN, USA; Division of General Internal Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Bjorg ThorsteinsdottirBiomedical Ethics Research Program, Mayo Clinic, Rochester, MN, USA; Division of Community Internal Medicine, Geriatrics and Palliative Care, Mayo Clinic, Rochester, MN, USA. Electronic address: Thorsteinsdottir.bjorg@mayo.edu.

Funding

Evidence Based Encounter Decision Aid for Elderly Patients to Promote Shared Decision Making on Treatment Choice in End Stage Renal DiseaseK23AG051679 · NIA · MAYO CLINIC ROCHESTER · PI THORSTEINSDOTTIR, BJOERG · 2016 to 2020
$908k
The Role of Patient Capacity in Chronic Kidney Disease TrajectoriesK01DK133643 · NIDDK · MAYO CLINIC ROCHESTER · PI Kasey Boehmer · 2023 to 2026
$601k
NCATS NIH HHS L30 TR002972NIA NIH HHS K23 AG051679NIDDK NIH HHS K01 DK133643
6 · The paper itself

Abstract

objectiveTo explore how older patients with chronic kidney disease (CKD) describe preferences for prognostic conversations.

methodsWe used reflexive thematic analysis to analyze transcripts of semi-structured interviews with CKD patients. Participants were recruited between July 2017 and November 2020.

resultsWe identified three major themes: (1) "To Know or Not: Honoring Patient Choices" encapsulates how prognostic conversations should center on the patient's preferences. (2) "Earlier or Later: Embracing Diverse Perspectives on Timing" underscores how each patient holds a unique perspective on the timing of prognosis discussions, and (3) "Navigating Uncertainty: Humanistic Qualities That Empower Healthcare Professionals to Support their Patients through Prognostic Conversations", highlights humanistic qualities that enable healthcare professionals to serve as sources of support for patients facing uncertainty during these conversations.

conclusionClinicians should proactively address the uncertainty of CKD by assessing patients' informational needs, understanding their experiences and values, and gauging their openness to advance care planning. Tailoring communication and fostering a strong clinical rapport can enhance patient engagement and support difficult conversations throughout the disease trajectory. PRACTICE IMPLICATIONS: We propose a mnemonic to help clinicians consider and implement these themes as they empower their patients to make health care decisions in the face of uncertainty. HOPE: Honoring patients' needs and wishes, Offering support, Promoting connections with careful and kind conversations and Exploring feelings and expectations. Clinicians should continue to strive for a strong human connection and provide prognostic information tailored to each patient's disease trajectory, needs and wishes.

Indexed as

Advance Care PlanningCommunicationPatient PreferencePhysician-Patient RelationsRenal Insufficiency, ChronicAgedAged, 80 and overDecision MakingFemaleHumansInterviews as TopicMaleMiddle AgedPrognosisQualitative ResearchUncertaintyChronic kidney diseaseCommunicationElderly patientsPrognosisUncertainty

Identifiers

PMID41764875
PMCPMC13046034

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.