ArticleNPJ Parkinson's disease2026
Beyond RBD: covert REM sleep abnormalities in Parkinson's disease.
Article in NPJ Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
REM sleep behavior disorder (RBD), involving REM sleep without atonia (RSWA), is a prodromal marker of Parkinson's disease (PD). We investigated whether RBD may represent the "tip of the iceberg" of pathology driving wider REM sleep disruptions. In this study, 25 early-stage, drug-naïve PD patients and 23 age-matched healthy controls underwent overnight polysomnography with high-density EEG (256 channels) to assess how sleep patterns relate to generalized motor learning (GML). PD patients showed no significant differences in overall sleep architecture but exhibited elevated RSWA levels, with 9 individuals (36% of the PD group) meeting criteria for excessive RSWA (PD
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