Evidence map›Paper›PMID 41764270›Full record

ArticleScientific reports2026

Cascaded regulatory network composed of small RNAs involves in the symbiosis of Panax notoginseng and fungus Acremonium sp. D212.

Baolin Yao, Haiyan Zhu, Xie He, Wenjing Yang, Chongyu Luo, Yan Li, Ao Yang, Yinhui Zhang, Lihui Jiang, Yaqiong Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Baolin Yao *CAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Yunnan Key Laboratory of Crop Wild Relatives Omics, State Key Laboratory of Plant Diversity and Specialty Crops, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Haiyan Zhu *College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Xie He *College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Wenjing YangCAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Yunnan Key Laboratory of Crop Wild Relatives Omics, State Key Laboratory of Plant Diversity and Specialty Crops, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Chongyu LuoCollege of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Yan LiCAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Yunnan Key Laboratory of Crop Wild Relatives Omics, State Key Laboratory of Plant Diversity and Specialty Crops, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Ao YangCollege of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Yinhui ZhangCollege of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Lihui JiangCollege of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Yaqiong LiCollege of Traditional Chinese Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China.
Liwei GuoCollege of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Xiahong HeYunnan Provincial Key Laboratory for Conservation and Utilization of In-Forest Resource, Southwest Forestry University, Kunming, 650224, Yunnan, China. hxh@swfu.edu.cn.
Yunlong DuCollege of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China. yunlongdu@aliyun.com.
Changning LiuCAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Yunnan Key Laboratory of Crop Wild Relatives Omics, State Key Laboratory of Plant Diversity and Specialty Crops, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China. liuchangning@xtbg.ac.cn.

Funding

the National Natural Science Foundation of China 32260085, 31660501,32570377
6 · The paper itself

Abstract

Panax notoginseng (P. notoginseng) is a valuable traditional Chinese medical herb with multiple pharmacological effects, and Acremonium sp. D212 is a symbiotic fungus. The symbiotic relationship between fungi and plants is widely present in nature, but the molecular mechanism of the symbiotic relationship between P. notoginseng and its symbiotic microorganisms is unknown. This study found that Acremonium sp. D212 altered the gene expression of P. notoginseng under different lights, and this change was associated with the miRNAs transferred from Acremonium sp. D212 to P. notoginseng. Transferred miRNAs can not only regulate P. notoginseng target genes, but also trigger the production of phased siRNAs to regulate more target genes, thereby forming a cascaded regulatory network. P. notoginseng target genes are associated with trans-membrane transporting and plant hormone metabolism, suggesting that these small RNAs may have potential influence on the growth and development of P. notoginseng. This study discovers an underlying molecular mechanism of the interactions between P. notoginseng and its symbiotic fungus Acremonium sp. D212, and provide a new perspective for further research on the gene interaction between plants and symbiotic fungi.

Indexed as

AcremoniumGene Expression Regulation, PlantPanax notoginsengRNA, FungalRNA, PlantGene Regulatory NetworksGenome, FungalSymbiosisTranscriptomeRNA, FungalRNA, PlantAcremonium sp. D212Panax notoginsengphasiRNARegulatory networkSymbiosis

Identifiers

PMID41764270
PMCPMC13057234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.