Evidence map›Paper›PMID 41764104›Full record

ArticleCardiovascular and interventional radiology2026

Feasibility of an Augmented Reality Artificial Intelligence Tool for Real-Time Assessment of Thyroid Fine-Needle Aspiration Adequacy.

Paul M Gibbs, Dat Xuan Nguyen, Gladys M Vargas, Michelle J Gibbs, Pranav Sudheesh, Emma K Fitzpatrick, Owen R Tapia, Josh Zhong, Julie B Steele

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul M GibbsScripps Memorial Hospital, La Jolla, CA, USA. gibbs.paul@scrippshealth.org.ORCID http://orcid.org/0000-0001-5831-3155
Dat Xuan NguyenV-Star Data, LLC, Hanoi, Vietnam.
Gladys M VargasSt. George's University School of Medicine, West Indies, Grenada.
Michelle J GibbsLeeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK.
Pranav SudheeshImperial College London School of Medicine, London, UK.
Emma K FitzpatrickDepartment of Pathology, Scripps Health, La Jolla, CA, USA.
Owen R TapiaDepartment of Pathology, Scripps Health, La Jolla, CA, USA.
Josh ZhongSt. George's University School of Medicine, West Indies, Grenada.
Julie B SteeleScripps Memorial Hospital, La Jolla, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the feasibility of developing an artificial intelligence application for real-time specimen adequacy assessment during ultrasound-guided fine needle aspiration of the thyroid gland using small, locally derived datasets and open-source AI tools. MATERIALS AND

methods1,244 photomicrographic images of thyroid needle aspiration slides were used to develop training and testing datasets for a YOLOv5 convolutional neural network model. In silico performance was tested for standard metrics. The model was deployed in an application featuring a live, augmented reality microscopy display. Hands-on testing was performed using a set of 50 blinded patient specimens tested in duplicate (N=100) by human observers with no prior formal training in pathology.

resultsOn an independent static image test set, the CNN achieved an AUROC of 0.954 (95% CI, 0.922-0.986) using images acquired with a dedicated microscope camera, with sensitivity 0.969, specificity 0.933, and accuracy 95.5%. Using images acquired with a smartphone camera, performance improved to an AUROC of 0.983 (95% CI, 0.965-1.000), with sensitivity 0.980, specificity 1.000, and accuracy 98.8%. In a simulated clinical workflow, human users assisted by the augmented reality AI tool demonstrated 96% concordance with the reference standard FNA adequacy assessment.

conclusionAn augmented reality microscopy tool based on a small-model CNN showed feasibility for performing real-time assessment of thyroid FNA specimen adequacy. Such a tool can enable telecytologic support of FNA assessment in radiologic facilities without an on-site pathologist.

Indexed as

Artificial IntelligenceAugmented RealityThyroid GlandBiopsy, Fine-NeedleConvolutional Neural NetworksFeasibility StudiesHumansIntelligent SystemsSensitivity and SpecificityUltrasonography, Interventionalartificial intelligenceaugmented reality microscopyconvolutional neural networkfine needle aspirationrapid onsite evaluationspecimen adequacythyroidUltrasound

Identifiers

PMID41764104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.