Evidence map›Paper›PMID 41763418›Full record

ArticleInternational journal of biological macromolecules2026

Ferritin iron uptake and oxidation are dynamically modulated by nucleotide phosphate architecture via electrostatic gating.

Anitha Rajendran, Sean Henley, Brent L Nannenga, Genki Terashi, Ayush Srivastava, Daisuke Kihara, Fadi Bou-Abdallah

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological macromolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anitha RajendranDepartment of Chemistry, State University of New York, Potsdam, NY, USA.
Sean HenleyDepartment of Chemistry, State University of New York, Potsdam, NY, USA.
Brent L NannengaChemical Engineering, School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, USA; Biodesign Center for Applied Structural Discovery, Biodesign Institute, Arizona State University, 727 East Tyler Street, Tempe, AZ, USA.
Genki TerashiDepartment of Biological Sciences, Purdue University, West Lafayette, IN, USA; Department of Computer Science, Purdue University, West Lafayette, IN, USA.
Ayush SrivastavaDepartment of Chemistry, State University of New York, Potsdam, NY, USA.
Daisuke KiharaDepartment of Biological Sciences, Purdue University, West Lafayette, IN, USA; Department of Computer Science, Purdue University, West Lafayette, IN, USA.
Fadi Bou-AbdallahDepartment of Chemistry, State University of New York, Potsdam, NY, USA. Electronic address: bouabdf@potsdam.edu.

Funding

Building protein structure models for intermediate resolution cryo-electron microscopy mapsR01GM133840 · NIGMS · PURDUE UNIVERSITY · PI KIHARA, DAISUKE · 2020 to 2023
$1.6M
Data-driven biomolecular structure modeling for cryo-EM mapsR35GM158267 · NIGMS · PURDUE UNIVERSITY · PI Daisuke Kihara · 2025 to 2026
$791k
NIGMS NIH HHS R01 GM133840NIGMS NIH HHS R35 GM158267
6 · The paper itself

Abstract

Ferritin safeguards cells from iron-induced oxidative stress by oxidizing and storing Fe

Indexed as

FerritinsIronNucleotidesPhosphatesCryoelectron MicroscopyHumansOxidation-ReductionStatic ElectricityFerritinsIronNucleotidesPhosphates3-Fold channelATP/nucleotidesCryo-EMElectrostatic gatingFerritinHydrationIron oxidationMetalloprotein regulation

Identifiers

PMID41763418
PMCPMC13276711

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.