ArticleEpilepsy research2026
Maternal pre-pregnancy body mass index, gestational weight gain and epilepsy in the offspring: A population-based cohort study.
Article in Epilepsy research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveThis study investigated whether maternal pre-pregnancy body mass index (BMI) and non-optimal gestational weight gain (GWG) are associated with epilepsy in the offspring. DESIGN, SETTING, POPULATION: We studied 3,816,438 children born between 2007 and 2015 ascertained from the California birth records.
main outcome measuresChildhood epilepsy was ascertained using the diagnostic records from the California's Department of Developmental Services.
methodsWe used generalized linear models to estimate the risk ratio (RR) and 95% confidence interval (CI) for childhood epilepsy according to maternal pre-pregnancy BMI (kg/m
resultsMaternal pre-pregnancy overweight (RR:1.12, 95% CI: 1.02-1.22) and obesity (RR:1.31, 95% CI: 1.20-1.44) were associated with higher risk of childhood epilepsy in the full cohort, with similar results observed among term births. No association was observed for maternal insufficient or excessive GWG and childhood epilepsy. Gestational weight loss (RR: 1.46, 95% CI: 1.15-1.86) was associated with childhood epilepsy among obese and overweight mothers, but the association became null among term births.
conclusionsWhile maternal pre-pregnancy overweight and obesity were modestly associated with childhood epilepsy in California, no clear pattern emerged for maternal non-optimal gestational weight gain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.