Evidence map›Paper›PMID 41762441›Full record

ArticleChembiochem : a European journal of chemical biology2026

Identification of ZFTA as a Novel KLHL20 Substrate and Mechanistic Insights Into Fuzzy Binding of Disordered Peptides via Biosensor Analysis and Computational Modelling.

Nadine E M Myers, Joanna Whittaker, Marie Elodie Hélène Cadot, Julia K Varga, Marcel Diallo, Jakob Nilsson, Anders Bach, Anja Sandström, Ora Schueler-Furman, U Helena Danielson

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nadine E M MyersDept. of Chemistry for the Life Sciences, Uppsala University, Uppsala, Sweden.ORCID 0009-0004-3440-2662
Joanna WhittakerDept. of Chemistry for the Life Sciences, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-0048-6392
Marie Elodie Hélène CadotDept. of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0009-0008-7954-2318
Julia K VargaDept. of Microbiology and Molecular Genetics, Institute for Biomedical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0002-5318-2798
Marcel DialloNovo Nordisk Foundation Center for Protein Research, ICMM, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0056-7333
Jakob NilssonNovo Nordisk Foundation Center for Protein Research, ICMM, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4100-1125
Anders BachDept. of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4305-9910
Anja SandströmDept. of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-5720-2904
Ora Schueler-FurmanDept. of Microbiology and Molecular Genetics, Institute for Biomedical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0002-1624-0362
U Helena DanielsonDept. of Chemistry for the Life Sciences, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-2728-0340

Funding

European Union's Horizon 2020 Research and Innovation program 860517Human Frontier Science Program LT0005/2022-CIsrael Academy of Sciences and Humanities 301/2021Israel Academy of Sciences and Humanities 3091/23Novo Nordisk Foundation Center for Protein Research NNF14CC0001The Danish National Research Foundation DNRF195
6 · The paper itself

Abstract

Interactions between peptides based on a region in the zinc finger translocation associated (ZFTA) protein and the Kelch domain of Kelch-like protein 20 (KLHL20

Indexed as

Biosensing TechniquesPeptidesAmino Acid SequenceHumansModels, MolecularProtein BindingSubstrate SpecificityPeptidesbiosensorcomputational designKelchKLHL20stapled peptide

Identifiers

PMID41762441
PMCPMC12949624

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.