Evidence map›Paper›PMID 41762377›Full record

ArticleVeterinary research communications2026

Swine inflammation and necrosis syndrome outbreak in Brazil: a case report.

Júlia Berro, Karoline Silveira Sperb, Gabriel Pola, Paola Reis Freimuth, Brendha Lauren Fetter, Daniela Teresa Schuh, Douglas Mikael Ribeiro da Rosa, Roberta Cristina Scheid, Karine Ludwig Takeuti

Abstract read
In one paragraph

Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Júlia BerroUniversidade Feevale, Novo Hamburgo, 93525-075, RS, Brazil.ORCID http://orcid.org/0009-0002-7961-9748
Karoline Silveira SperbUniversidade Feevale, Novo Hamburgo, 93525-075, RS, Brazil.
Gabriel PolaUniversidade Feevale, Novo Hamburgo, 93525-075, RS, Brazil.
Paola Reis FreimuthUniversidade Feevale, Novo Hamburgo, 93525-075, RS, Brazil.
Brendha Lauren FetterUniversidade Feevale, Novo Hamburgo, 93525-075, RS, Brazil.
Daniela Teresa SchuhCooperativa Ouro do Sul, Harmonia, RS, Brazil.
Douglas Mikael Ribeiro da RosaCooperativa Ouro do Sul, Harmonia, RS, Brazil.
Roberta Cristina ScheidCooperativa Ouro do Sul, Harmonia, RS, Brazil.
Karine Ludwig TakeutiUniversidade Feevale, Novo Hamburgo, 93525-075, RS, Brazil. karinelt87@yahoo.com.br.ORCID http://orcid.org/0000-0002-4901-1013

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak occurred in three farrowing rooms from a commercial farrow-to-wean farm with 4,600 sows located in southern Brazil. During the first week of outbreak, diarrhea and vomiting were recorded in sows, and inflammatory lesions were reported in neonatal piglets. Lesions were located on the tail, hock, perineal area, teats, vulva, male genital organs, sole, coronary band, ear, and jaw, which progressed to necrosis within few days. A total of 562 sows were evaluated for the presence of diarrhea and vomiting. Their litters, comprising 8,344 suckling piglets, were individually assessed for the presence, location and type of lesions. Laboratory analysis confirmed the presence of ergosterol in feed, which indicates a poor microbiological stability and fungal yeast invasion of the feed. Diarrhea was observed in 2.3% of sows. Overall, 38.2% (n = 3,190) of piglets presented lesions. In farrowing unit A, the tail and claw were the most frequently affected areas, whereas sole lesions predominated in room B and teat lesions in room C. Additionally, 12.0% of piglets born from sows with high genetic potential were not selected for replacement due to teats necrosis. This is the first case report of Swine Inflammation and Necrosis Syndrome (SINS) described outside Europe. Moreover, it highlights the importance of early diagnosis and feed monitoring for the prevention of mycotoxicosis in swine, to reduce their impacts on animal welfare, gilt selection for replacement, and removal of contaminated feed from the farm.

Indexed as

Disease OutbreaksInflammationNecrosisSwine DiseasesAnimal FeedAnimalsAnimals, NewbornBrazilFemaleSwineFeedMycotoxinsSINSSwine

Identifiers

PMID41762377
PMCPMC12950095

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.