Evidence map›Paper›PMID 41762335›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

Significance of geriatric nutritional risk index in predicting lung-transplant waiting list mortality of patients with interstitial lung disease regardless of percentage forced vital capacity.

Chihiro Konoeda, Gouji Toyokawa, Miho Yamaguchi, Takafumi Yamaya, Takaki Aakamine, Mitsuaki Kawashima, Mototsugu Shimokawa, Masaaki Sato

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Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Chihiro Konoeda *Department of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Gouji Toyokawa *Department of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Miho YamaguchiDepartment of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Takafumi YamayaDepartment of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Takaki AakamineDepartment of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Mitsuaki KawashimaDepartment of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Mototsugu ShimokawaDepartment of Biostatistics, Graduate School of Medicine, Yamaguchi University, Yamaguchi, Japan.
Masaaki SatoDepartment of Thoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. SATOM-SUR@h.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0003-1693-8573

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe geriatric nutritional risk index (GNRI) is derived from serum albumin, current body weight, and ideal body weight. It is a prognostic indicator for waitlist mortality in patients awaiting lung transplantation (LT). However, its significance according to respiratory function in patients with interstitial lung disease (ILD) awaiting LT remains unclear.

methodsWe retrospectively analyzed adult patients with ILD listed for LT from donation after brain death between January 2014 and July 2024. They were divided into two groups based on a cutoff of 50% for percentage forced vital capacity (%FVC). A GNRI cutoff value of 93.84 was established based on our previous study.

resultsAmong 253 patients, 123 (48.6%) underwent LT, 81 (32.0%) died while awaiting LT, and 49 (19.4%) remained on the waiting list. The high- and low-%FVC groups included 123 (48.6%) and 130 patients (51.4%), respectively. In the high-%FVC group, 105 (85.4%) and 18 (14.6%) patients had a high and low GNRI, respectively. In the low-%FVC group, 78 (60.0%) and 52 (40.0%) patients had a high and low GNRI, respectively. In both groups, patients with a low GNRI had significantly shorter survival compared with those having a high GNRI (both P = 0.001). In multivariate analyses, low GNRI was an independent predictor of poor prognosis in both the high- and low-%FVC groups (hazard ratio = 4.918 and 2.576, P < 0.001 and = 0.001, respectively).

conclusionsThe GNRI may serve as a prognostic factor for waitlist mortality in patients with ILD awaiting LT, regardless of %FVC.

Indexed as

Geriatric AssessmentLung Diseases, InterstitialLung TransplantationNutritional StatusNutrition AssessmentWaiting ListsAgedAge FactorsFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentGeriatric Nutritional Risk IndexInterstitial lung diseaseLung transplantationRespiratory function

Identifiers

PMID41762335
PMCPMC13283179

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.