Observational studySleep & breathing = Schlaf & Atmung2026
Associations Between Obstructive Sleep Apnea, Obesity, and Indices of Cardiovascular Health Among a Cross-Sectional Sample of Adults Residing in the Southeastern United States.
Observational study in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeCardiovascular disease is among the most common diseases in the United States; however, relationships between obstructive sleep apnea (OSA), obesity, and cardiovascular health are not fully understood. This study aimed to examine differences in OSA severity and cardiovascular health indices across body mass index (BMI) classifications, and to investigate associations among OSA, BMI, and arterial stiffness in a sample of adults from the southeastern United States.
methodsThis analysis is part of the ongoing Short Sleep Undermines Cardiometabolic Health-Public Health Observational Study (SLUMBRx-PONS) study. Data included 75 adults assessed for anthropometrics, OSA severity, quantified via apnea-hypopnea index (AHI), and noninvasive cardiovascular health indices including resting mean arterial pressure (MAP), carotid-femoral pulse wave velocity (cfPWV), and augmentation index (AIx75).
resultsCompared to individuals at normal weight, adults with obesity presented with significantly higher AHI, MAP, cfPWV, and AIx75 values. While AHI and cfPWV were not directly associated, after adjusting for sex and MAP, we found a BMI-mediated negative association between age and cfPWV, which was strongest among younger adults with elevated BMI. Additionally, adjusting for age and MAP, AHI was positively associated with AIx75, also mediated by BMI, with the greatest effect observed at higher BMI levels.
conclusionThese results suggest that obesity is a key contributor to poor cardiovascular health in the southeastern United States. Moreover, the relationship between OSA and arterial stiffness may be BMI-dependent and varies by measurement selection. Obesity and measurement selection should be primary considerations for arterial stiffness in cardiovascular risk assessment.
Indexed as
Identifiers
41762331What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.