ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Prevalence of concurrent severe self-reported late symptoms and functional limitations in cancer survivors: a cross-sectional study of sociodemographic, clinical, and lifestyle associations.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
purposeThis population-based study investigated the prevalence of concurrent severe symptoms and functional limitations among Danish cancer survivors, examining associations with sociodemographic, clinical, and lifestyle factors.
methodsWe conducted a cross-sectional analysis using data from the nationwide SEQUEL questionnaire study (2022), including 40,766 survivors 2- to 12-year post-diagnosis (2010-2019). Up to 21 symptoms, five functioning domains, and sexual satisfaction were assessed using validated instruments (EORTC QLQ-C30, EORTC Item Library, QLQ-SHQ22, GAD-7, PHQ-9). Data were obtained from Danish registries, clinical databases, and self-report. Symptoms and functional limitations were categorized as severe using predefined thresholds. Ordinal logistic regression models examined factors associated with concurrent symptoms.
resultsMean symptom count was 4.1 for women (range 0-21, SD 3.19) and 3.3 for men (range 0-20, SD 2.72), with 25% of women and 16% of men experiencing ≥ 5 concurrent severe symptoms. Lung cancer survivors reported the highest symptom burden. Factors significantly associated with concurrent symptoms included short education, lower income, living alone, multiple comorbidities (CCI ≥ 2), advanced disease, palliative treatment, current smoking, and higher BMI, with ORs ranging from 1.29-2.19 (women) and 1.23-2.25 (men). Impaired functioning showed similar associations.
conclusionConcurrent late symptoms are common among cancer survivors, indicating complex health issues varying by cancer type and clinical characteristics, with clear socioeconomic disparities and lifestyle associations. These findings highlight subgroups who may benefit from interventions targeting multiple symptoms and underscore the importance of addressing social determinants and lifestyle factors in survivorship care.
Indexed as
Identifiers
41762307What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.