Evidence map›Paper›PMID 41762298›Full record

SynthesisJournal of cancer research and clinical oncology2026

Personalizing cancer risk: a systematic review of risk communication strategies.

Akila Anandarajah, Rachelle Roy, Grace Cross, Carolyn Stoll, Angela Hardi, Shu Jiang, Graham A Colditz, Ashley J Housten

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of cancer research and clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Missing Dimension in Cancer Education: Developmental Meaning-Making and the Expert's Illusion of Symmetry.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Akila AnandarajahDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-0430-9561
Rachelle RoyDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Grace CrossDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Carolyn StollDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-6951-4219
Angela HardiBernard Becker Medical Library, Washington University School of Medicine, MO, St. Louis, USA.ORCID http://orcid.org/0000-0001-5693-8979
Shu JiangDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-1464-4838
Graham A ColditzDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-7307-0291
Ashley J HoustenDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA. ahousten@wustl.edu.ORCID http://orcid.org/0000-0002-7379-0678

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
NCATS NIH HHS UL1TR002345
6 · The paper itself

Abstract

Purpose: Personalized risk communication (PRCom) can help individuals make informed decisions about electing to undergo cancer screening based on their specific risk. In this systematic review, we examined existing risk communication strategies used in the presentation of PRCom and how they may impact screening-related cognitive and behavioral outcomes. Methods: We searched Embase.com, Ovid-Medline All, Scopus, CINAHL Complete, and CENTRAL Trials (via Cochrane Library) for randomized controlled trials addressing interventions with an element of “personalized” cancer risk communication based on the individual’s risk factors. Results: Eighteen unique studies were included. From these 18 studies, we extracted data on PRCom presentation methods and outcome measures such as knowledge and screening completion. Text was used in the majority of PRCom (56%, n = 10), followed by graphs (39%, n = 7), icon arrays (17%, n = 3), charts (17%, n = 3), graphics (17%, n = 3), and video (6%, n = 1). None of these studies included direct format comparisons. We found that knowledge of risk increased in scenarios where PRCom: 1) combined visual (e.g., videos) and text-based communication; and 2) used verbatim (4/5), rather than gist communication (2/7). Screening completion also increased for PRCom with both visual and text-based communication (3/4). However, knowledge of risk and screening completion were minimally impacted if PRCom used only text/verbal communication (1/3 for knowledge of risk, 0/2 for screening completion) or only visual aids (1/3 for knowledge of risk, 2/5 for screening completion). Conclusion: Future research examining the translation of communication strategies to screening-related cognitive and behavioral outcomes is warranted.

Indexed as

CommunicationNeoplasmsPrecision MedicineEarly Detection of CancerHumansRisk AssessmentRisk FactorsCancerCancer preventionCancer riskCancer screeningPersonalized riskRisk communication

Identifiers

PMID41762298
PMCPMC12950128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.