Evidence map›Paper›PMID 41762261›Full record

ArticleEuropean radiology2026

Dual-plane taller-than-wide definition for thyroid nodules: comparative analysis across TIRADS.

Yu Zhuang, Jiamin Chen, Jing Zhong, Qixin Wen, Shanshan Ran, Bixue Deng, Jiayi Hong, Qingan Zeng, Lin Liu, Xin Wen

Abstract readComparative Study
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In one paragraph

Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yu ZhuangDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China.
Jiamin ChenDepartment of Ultrasound, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Jing ZhongDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China.
Qixin WenDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China.
Shanshan RanDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China.
Bixue DengDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China.
Jiayi HongDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China.
Qingan ZengDepartment of Thyroid and Breast Surgery, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China. zengqa@mail.sysu.edu.cn.
Lin LiuDepartment of Thyroid and Breast Surgery, The Sixth School of Clinical Medicine, the Affiliated Qingyuan Hospital (Qingyuan People's Hospital), Guangzhou Medical University, Qingyuan, China. liulin86819@163.com.
Xin WenDepartment of Ultrasound, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, China. wenxin7@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-5701-7941

Funding

Natural Science Foundation of Xinjiang Uygur Autonomous Region 82202168
6 · The paper itself

Abstract

objectivesThe selection of ultrasound (US) plane for evaluating the taller-than-wide (TTW) shape remains controversial. This study aimed to determine whether the diagnostic value of TTW criteria differs when used alone or in combination with other US features, and to identify the optimal TTW criterion across four major Thyroid Imaging Reporting and Data Systems (TIRADS: Chinese (C)-TIRADS, American College of Radiology (ACR)-TIRADS, European (EU)-TIRADS and Korean (K)-TIRADS). MATERIALS AND

methodsPreoperative US images of thyroid nodules were reviewed retrospectively. Four TTW criteria were defined as follows: transverse plane only (T-only), longitudinal plane only (L-only), both planes (Dual-plane), and either one or both planes (Single- or dual-plane). Diagnostic performance was assessed using the area under the receiver operating characteristic curve (AUC) and net reclassification improvement (NRI) for malignancy prediction and fine-needle aspiration (FNA) guidance.

resultsAmong 1125 nodules, 558 (49.6%) were benign and 567 (50.4%) were malignant. Using the TTW shape alone, Single- or dual-plane achieved the highest AUC for malignancy (0.813). Within TIRADS, Dual-plane demonstrated the highest AUCs in C-TIRADS (0.884) and EU-TIRADS (0.874) and improved reclassification, whereas in ACR-TIRADS and K-TIRADS, Dual-plane and Single- or dual-plane performed similarly and outperformed the T-only and L-only. For FNA guidance, the Dual-plane also showed improvements in C-TIRADS and ACR-TIRADS.

conclusionThe optimal TTW US plane differs when applied alone versus when combined with other suspicious US features. Within the TIRADS, assessment of the TTW shape in both transverse and longitudinal planes achieves superior accuracy and contributes to improving malignancy diagnosis and FNA decision-making. KEY POINTS: Question Which TTW criterion provides the best diagnostic performance for malignancy risk stratification and FNA guidance across the four major TIRADS? Findings Dual-plane TTW yielded the best performance in C-TIRADS and EU-TIRADS, and improved FNA guidance in C-TIRADS and ACR-TIRADS versus other TTW criteria. Clinical relevance The stricter criterion not only improves the malignancy diagnosis but also provides better guidance for biopsy, offering valuable evidence for refining future guideline recommendations and standardizing the evaluation of thyroid nodules.

Indexed as

Thyroid NoduleAdultAgedBiopsy, Fine-NeedleFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityUltrasonographyBiopsyTaller-than-wideThyroid noduleTIRADSUltrasonography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.