Evidence map›Paper›PMID 41762234›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2026

Gene mapping and identification of candidate genes associated with fomesafen herbicide tolerance in Mung bean (Vigna radiata L.).

Huiying Shi, Changyou Liu, Shen Wang, Yan Wang, Zhixiao Zhang, Yingchao Shen, Sivakumar Paramasivam, Jing Tian, Baojie Fan

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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Huiying Shi *Institute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China.
Changyou Liu *Institute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China.
Shen Wang *Institute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China.
Yan WangInstitute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China.
Zhixiao ZhangInstitute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China.
Yingchao ShenInstitute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China.
Sivakumar ParamasivamAgricultural College and Research Institute, Tamil Nadu Agricultural University, Thanjavur, 614902, India.
Jing TianInstitute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China. nkytianjing@163.com.
Baojie FanInstitute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Hebei Key Laboratory of Crop Genetics and Breeding, Shijiazhuang, 050035, China. fanbaojie1972@163.com.ORCID http://orcid.org/0009-0008-3675-9509

Funding

China Agriculture Research System of MOF and MARA-Food Legumes CARS-08Hebei Agriculture Research System-Innovation Team of Coarse Cereals and Food Legume HBCT2023050205Hebei Seed Science and Technology Innovation Team of Coarse Cereals and Food Legumes 21326305DInnovation Special Project of Hebei Academy of Agriculture and Forestry Sciences 2022KJCXZX-LYS-17National Natural Science Foundation of China 32401885
6 · The paper itself

Abstract

key messageThrough an integrated approach of genetic mapping, transcriptomics, and functional validation, we identified VrGSTU18 as the primary gene associated with fomesafen resistance in mung bean, providing a genetic resource for breeding herbicide-resistant varieties. Herbicides are widely applied for weed control in mung bean cultivation, and the development of new varieties with herbicide resistance is critical for weed management. In this study, a recombinant inbred line (RIL) population, derived from a cross between the fomesafen-resistant variety LZ177 and susceptible variety LD235, was used to map the genes related to fomesafen herbicide resistance. Genetic segregation analysis indicated that fomesafen resistance is controlled by a single dominant gene, following a 3:1 ratio. Genetic mapping combined BSA-seq revealed a candidate region of 1.17 Mb on chromosome 11. RNA-seq analysis of residual heterozygous line 198-comparing resistant (RHL198-R) and susceptible (RHL198-S) bulks at 0, 12, 24, 48, and 72 h after fomesafen treatment-identified 14,402 herbicide-responsive genes. Weighted gene coexpression network analysis (WGCNA) further identified nine modules highly correlated with fomesafen resistance, of which 13 potential candidate genes were selected within the 1.17 Mb interval. Among these, one-base (A) insertion/deletion in the exon of jg37117, which encode a tau-class glutathione S-transferase U18 (GSTU18), emerged as the most promising candidate gene. Heterologous expression of VrGSTU18 cloned from LZ177 in Arabidopsis conferred enhanced fomesafen resistance in T

Indexed as

Genes, PlantHerbicide ResistanceHerbicidesVignaBenzamidesChromosome MappingGene Expression Regulation, PlantPlant ProteinsBenzamidesfomesafenHerbicidesPlant ProteinsFomesafen toleranceGlutathione S-transferase U18Mung beanTransgenic validation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.