Evidence map›Paper›PMID 41761878›Full record

ArticleGut microbes2026

Myosin IIA motor regulates attaching-effacing bacteria interactions with intestinal epithelium.

Nayden G Naydenov, Atif Zafar, Susana Lechuga, Ajay Zalavadia, Armando Marino-Melendez, John A Hammer, Velia M Fowler, Christine McDonald, Kenneth G Campellone, Andrei I Ivanov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nayden G NaydenovDepartment of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.
Atif ZafarDepartment of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.
Susana LechugaDepartment of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.
Ajay ZalavadiaDepartment of Molecular Medicine, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Case Western Reserve University, Cleveland, OH, USA.
Armando Marino-MelendezDepartment of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.
John A HammerCell and Developmental Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Velia M FowlerDepartment of Biological Sciences, University of Delaware, Newark, DE, USA.
Christine McDonaldDepartment of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.
Kenneth G CampelloneDepartment of Molecular & Cell Biology and Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA.
Andrei I IvanovDepartment of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0003-4823-209X

Funding

Novel cytoskeletal mechanisms of pathogenic bacteria interactions with intestinal epitheliumR01DK131550 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI Andrei Ivanovich Ivanov · 2022 to 2026
$2.5M
Leica TCS SP8 Confocal Microscope for a Core FacilityS10OD019972 · OD · CLEVELAND CLINIC LERNER COM-CWRU · PI DRAZBA, JUDY · 2015 to 2015
$544k
NIDDK NIH HHS R01 DK131550NIH HHS S10 OD019972
6 · The paper itself

Abstract

Attaching effacing (A/E) bacteria, such as enteropathogenic

Indexed as

Bacterial AdhesionCitrobacter rodentiumEnteropathogenic Escherichia coliIntestinal MucosaNonmuscle Myosin Type IIAAnimalsCaco-2 CellsEpithelial CellsHumansMiceMice, Inbred C57BLMice, KnockoutNonmuscle Myosin Type IIAactin cytoskeletonattaching/effacing bacteriaintestinal epitheliumMyosin II

Identifiers

PMID41761878
PMCPMC12959189

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.