ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Sustainable Phosphorylated Cellulose Nanocrystals: A Dual-Affinity Platform for High-Efficiency Enrichment of Intact Glycopeptides and Phosphopeptides.
Jiaying Li, Wuming Fan, Xuyang Yue, Dongdong Wang, Xiangyu Tang, Zhuo Zhang, Yonggui Wang, Yanjun Xie, Mingliang Ye, Hongqiang Qin
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Jiaying LiCollege of Materials Science and Engineering, Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.
Wuming FanCollege of Materials Science and Engineering, Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.
Xuyang YueCAS Key Laboratory of Separation Science For Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Dongdong WangCollege of Materials Science and Engineering, Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.
Xiangyu TangCollege of Materials Science and Engineering, Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.
Zhuo ZhangState Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, China.
Yonggui WangCollege of Materials Science and Engineering, Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.ORCID https://orcid.org/0000-0002-5135-1367 Yanjun XieCollege of Materials Science and Engineering, Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.
Hongqiang QinState Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, China.
Funding
Dalian Science Foundation for Distinguished Young Scholars 2023RJ011Fundamental Research Funds DUT25YG252Fundamental Research Funds DUT25YG270National Key Research and Development Program of China 2022YFC3400801National Key Research and Development Program of China 2023YFD2200503National Natural Science Foundation of China 22222409National Natural Science Foundation of China 22474137National Natural Science Foundation of China 92253301
6 · The paper itselfAbstract
Protein glycosylation and phosphorylation are critical post-translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials. Herein, we report a green synthesis of phosphorylated cellulose nanocrystals (P-CNCs) via one-step phosphoric acid hydrolysis, enabling dual-affinity enrichment of both glycopeptides and phosphopeptides. P-CNCs leverage abundant surface hydroxyl groups for hydrophilic interaction liquid chromatography (HILIC)-based glycopeptide capture, and intrinsic phosphate groups enable direct Ti
Indexed as
CelluloseGlycopeptidesNanoparticlesPhosphopeptidesAnimalsGlycosylationHumansMicePhosphorylationProtein Processing, Post-TranslationalProteomicsCelluloseGlycopeptidesPhosphopeptidesdual‐affinity enrichmentglycoproteomicsphosphoproteomicsphosphorylated cellulose nanocrystalspost‐translational modifications (PTMs)
Identifiers
PMID41761620
PMCPMC13170199
What OpenQuestion holds
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LicenceCC BY
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