ArticleJournal of applied clinical medical physics2026
An X-ray and γ-ray combination strategy to exploit steep dose gradients for improved prostate cancer radiotherapy: A dosimetric comparison of Taichi Pro and Halcyon.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aimed to evaluate a novel technological platform, Taichi Pro-which integrates a 6 MV flattening filterfree linear accelerator with a 18 source Rotating Gamma System (RGS) to generate steep dose gradients via multisource focused γ-rays and noncoplanar arcs-for precision radiotherapy in prostate cancer. The work provides evidence to support the clinical adoption of hybridmodality radiotherapy devices.
methodsFifteen prostate cancer patients were enrolled. For each patient, a dual-modality Taichi Pro plan (RGS focused on the planning gross tumor volume (PGTV) + Linac covering the planning target volume (PTV)) and a Halcyon photon plan (three-arc VMAT) were designed while maintaining clinically tolerable dose to organs at risk (OAR). Comparative assessments included planning target volume (PTV and PGTV) metrics (D
resultsAll plans met institutional clinical constraints. Taichi Pro significantly increased PGTV D
conclusionUtilizing the steep dose gradient characteristic of the RGS, the Taichi Pro dual-modality system effectively achieved target dose escalation while simultaneously improving sparing of adjacent OARs. This approach holds the potential for enhancing patient treatment outcomes and quality of life.
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