Evidence map›Paper›PMID 41761575›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2026

Impact of national partnership to improve dementia care on antipsychotic use duration for dementia residents in nursing homes.

Theresa I Shireman, Corinne Roma, Andrew R Zullo, Antoinette B Coe, Lori A Daiello, Christopher J Liu, Derrick Lo, Julie P W Bynum, Lauren B Gerlach

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Theresa I ShiremanCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, United States.ORCID 0000-0001-6846-8783
Corinne RomaCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, United States.
Andrew R ZulloCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, United States.ORCID 0000-0003-1673-4570
Antoinette B CoeInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, United States.
Lori A DaielloCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, United States.ORCID 0000-0003-3159-8597
Christopher J LiuCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, United States.ORCID 0009-0001-6201-1077
Derrick LoCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, United States.
Julie P W BynumInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, United States.
Lauren B GerlachInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-1943-0150

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
Clinically Significant Drug Interactions among Nursing Home Residents with ADRDR01AG077620 · NIA · BROWN UNIVERSITY · PI Andrew Reis Zullo · 2022 to 2026
$3.5M
Prescribing Cascades among Nursing Home Residents with ADRDRF1AG089541 · NIA · BROWN UNIVERSITY · PI HAYES, KALEEN NICOLE, ZULLO, ANDREW REIS · 2024 to 2024
$2.2M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Post-Acute Care Medication Use and Functional Recovery in Heart FailureR01AG088522 · NIA · BROWN UNIVERSITY · PI PARAG GOYAL, Andrew Reis Zullo · 2024 to 2026
$1.9M
National study of antiepileptic use among patients with dementia in long-term careR01AG087073 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lauren Beth Gerlach · 2025 to 2026
$1.4M
Medicating distress: Use of psychotropic medications among patients with dementia receiving hospice careK23AG066864 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GERLACH, LAUREN BETH · 2021 to 2025
$1.0M
Improving Medication Use and Outcomes in Older Adults with Dementia after Hospitalization: Effectiveness of Medicare ProgramsK08AG071856 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COE, ANTOINETTE BARTOLOTTA · 2021 to 2024
$620k
NIA NIH HHS K08 AG071856NIA NIH HHS K23AG066864NIA NIH HHS P01 AG027296NIA NIH HHS R01AG065722NIA NIH HHS R01AG077620NIA NIH HHS R01AG087073NIA NIH HHS R01AG088522NIA NIH HHS RF1AG089541
6 · The paper itself

Abstract

backgroundFederal policies have successfully targeted the prevalence of antipsychotic (AP) exposure in NHs, but the duration of treatment among nursing home (NH) residents has not been reported. We evaluated AP duration and discontinuation within six months in residents with dementia.

methodsRetrospective cohort study of long-stay NH residents with dementia who newly initiated an AP medication. We evaluated changes in AP duration and discontinuation within six months relative to two federal initiatives: National Partnership to Improve Dementia Care (2012) and inclusion of AP use measures in the NH Star Ratings (2015). We accounted for resident and facility characteristics in a competing-risks analysis establishing the relationship between the two policy periods and AP outcomes.

resultsThere were 43 668 new episodes of AP initiation among 38 275 residents. The duration of treatment within six months declined from 125.9 days in the pre-Partnership period to 120.5 days and 120.6 days in the post-Partnership and post-Five Star periods, respectively. Those who initiated APs after the Partnership [adjusted hazard ratio (aHR) = 1.17; confidence interval, 1.10-1.24] and after the Five Star Rating change (aHR = 1.19; 95% CI, 1.07-1.32) policy periods were more likely to stop the medication within 6 months as compared to those who initiated during the prior period.

conclusionsFederal policies designed to reduce AP prescribing in NH residents with dementia had a nominal impact on treatment duration within the first six months, with more than half continuing treatment beyond 6 months.

Indexed as

Antipsychotic AgentsDementiaNursing HomesAgedAged, 80 and overFemaleHumansMaleNursing Home ResidentsRetrospective StudiesTime FactorsUnited StatesAntipsychotic AgentsAntipsychoticsDementiaHealth policyNursing homes

Identifiers

PMID41761575
PMCPMC13014163

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.