Evidence map›Paper›PMID 41761561›Full record

ArticleJNCI cancer spectrum2026

A process evaluation of early palliative care implementation in the National Cancer Institute Community Oncology Research Program.

Lisa Zubkoff, Elizabeth Carpenter-Song, Kathleen Doyle Lyons, J Nicholas Odom, Sarah Khalidi, Andres Azuero, Marie Flannery, Richard Taylor, Jaimie Richards, Karen Mustian and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in JNCI cancer spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04062552 (Implementing Palliative Care), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04062552 naactive not recruitingnot on this map

Implementing Palliative Care: Learning Collaborative vs. Technical Assistance

TypeinterventionalSponsorUniversity of Rochester NCORP Research BaseRan2021 to 2026Enrolled208ConditionsAdvanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid NeoplasmArmsBehavioral, Psychological or Informational Intervention, Educational Intervention, Medical Examination Assessment, Quality-of-Life Assessment, Survey Administration
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lisa ZubkoffDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0002-0728-2237
Elizabeth Carpenter-SongDepartment of Anthropology, Dartmouth College, Hanover, NH, United States.
Kathleen Doyle LyonsDepartment of Occupational Therapy, Massachusetts General Hospital Institute of Health Professions, Boston, MA, United States.ORCID 0000-0002-8895-4612
J Nicholas OdomSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0001-6764-0254
Sarah KhalidiSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.
Andres AzueroSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0001-9883-1424
Marie FlannerySchool of Nursing, University of Rochester Cancer Center, National Cancer Institute Community Oncology Research Program (NCORP) Research Base, Rochester, NY, United States.
Richard TaylorDepartment of Medicine, Division of Gerontology, Geriatrics and Palliative Care, Center for Palliative and Supportive Care, University of Alabama at Birmingham, Birmingham, AL, United States.
Jaimie RichardsDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0003-3596-8284
Karen MustianDepartment of Surgery, Wilmot Cancer Institute, University of Rochester Cancer Center, National Cancer Institute Community Oncology Research Program (NCORP) Research Base, Rochester, NY, United States.ORCID 0000-0001-6525-7518
Megan WellsWilmot Cancer Institute, University of Rochester Cancer Center, National Cancer Institute Community Oncology Research Program (NCORP) Research Base, Rochester, NY, United States.
Judy HancockCancer Research for the Ozarks NCORP, Springfield, MO, United States.
Mark WojtowiczOncology Research and Innovation, Geisinger Cancer Institute NCORP, Danville, PA, United States.ORCID 0000-0003-2892-9404
Matthias WeissWisconsin NCORP at ThedaCare, Appleton, WI, United States.ORCID 0000-0003-2744-0973
Supriya MohileDepartment of Medicine, Division of Hematology/Oncology, Wilmot Cancer Institute, University of Rochester Cancer Center, National Cancer Institute Community Oncology Research Program (NCORP) Research Base, Rochester, NY, United States.ORCID 0000-0003-0867-327X
Marie Anne BakitasSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, United States.

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Implementing Palliative Care: Learning Collaborative vs. Technical AssistanceR01CA229197 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZUBKOFF, LISA · 2018 to 2024
$3.0M
National Cancer Institute of the National Institutes of Health R01CA229197NCI NIH HHS R01 CA229197NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

backgroundCare delivery trials to integrate early palliative care in community oncology practices are needed to enhance guideline-concordant care; however, little is known about how to successfully implement these trials within national research networks.

methodsA process evaluation was conducted to identify and address practice and patient recruitment challenges within a nationwide cluster randomized trial testing 2 implementation strategies (virtual learning collaborative vs technical assistance) for integrating the Educate, Nurture, Advise, Before Life Ends (ENABLE) early palliative care program in the National Cancer Institute Community Oncology Research Program. To examine implementation barriers, we collected quantitative practice and clinician characteristics via surveys and conducted qualitative interviews with clinicians and staff. Interview data were coded and summarized using content analyses to identify barriers to implementing study procedures and the ENABLE program.

resultsSurveys and interviews were completed by 33 clinicians, 23 ENABLE coaches, and 19 coordinators in 9 practice clusters between April 2021 and June 2022. Although 78% of practice clusters identified availability of some palliative care services, none routinely referred all newly diagnosed advanced cancer patients to these services as recommended by guidelines. Key research and clinical ENABLE implementation barriers included limited staffing during and after COVID-19, low physician buy-in, belief that ENABLE overlapped with existing palliative services, and participant burden. In response, several trial modifications were made to enhance flexibility with study procedures and the clinical ENABLE intervention.

conclusionsImplementation trials within cancer clinical trial networks must employ pragmatic and iterative study procedures to accommodate clinical practice workflows.

trial registrationClinicalTrials.gov Identifier: NCT04062552.

Indexed as

Medical OncologyNeoplasmsPalliative CareProcess Assessment, Health CareHumansNational Cancer Institute (U.S.)Patient SelectionProgram EvaluationRandomized Controlled Trials as TopicUnited States

Identifiers

PMID41761561
PMCPMC13076938

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.