Evidence map›Paper›PMID 41760812›Full record

ArticleApplied microbiology and biotechnology2026

Development of novel microbial synthetic consortia for the production of antimicrobial fermentates containing caproate.

Maria Florencia Bambace, Ker Sin Ng, Kirsten Wiborg Jensen, Adrien Schneider, Mensure Elvan Gezer, Angeliki Marietou, Aviaja Kristiansen Aarseth, Annika Regnet, Kathrine Gravlund Fønss, Ulrik Kræmer Sundekilde and 1 more

Abstract read
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In one paragraph

Article in Applied microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria Florencia Bambace *Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Ker Sin Ng *Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Kirsten Wiborg JensenDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Adrien SchneiderDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Mensure Elvan GezerDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Angeliki MarietouDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Aviaja Kristiansen AarsethDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Annika RegnetDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Kathrine Gravlund FønssDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Ulrik Kræmer SundekildeDepartment of Food Science, Aarhus University, Aarhus, Denmark.
Clarissa SchwabDepartment of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark. schwab@bce.au.dk.

Funding

Novo Nordisk Fonden NNF21OC0066725
6 · The paper itself

Abstract

Short- and medium chain carboxylic acids (SCCA/MCCA) are natural antimicrobials produced by fermentation and chain elongation, but currently only a few SCCA/MCCA are used in food-related applications. With the aim to diversify the SCCA/MCCA profile of fermentates for biopreservation, we designed bioprocesses employing bacterial or multi-kingdom consortia to produce caproate-containing fermentates using a targeted cross-feeding strategy. We combined Limosilactobacillus reuteri, Clostridium kluyveri, and Saccharomyces cerevisiae, and quantified substrates utilization and metabolites. The antimicrobial activity of SCCA/MCCA and fermentates was analysed in vitro and in a meat model system. In a first bioprocess, the addition of ethanol (EtOH) initiated caproate formation by the bacterial consortium with levels of 63.9 mM (7.4 g L

Indexed as

Anti-Infective AgentsCaproatesMicrobial ConsortiaBacteriaCarboxylic AcidsClostridium kluyveriEthanolFermentationSaccharomyces cerevisiaeAnti-Infective AgentsCaproatesCarboxylic AcidsEthanolAntimicrobial activityBioreactor fermentationCaproateC. kluyveriCross-feedingMulti-kingdom consortium

Identifiers

PMID41760812
PMCPMC12950656

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.