Evidence map›Paper›PMID 41760674›Full record

ArticleScientific reports2026

Dosimetric comparison of DIBH and FB for left-sided breast cancer radiation therapy.

Yao Wang, Chang Liu, Ruigang Ge, Wei Yu, Chuanbin Xi, Lingling Meng, Weiwei Yan, Zhongjian Ju, Lin Ma, Baolin Qu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yao WangDepartment of General Internal Medicine, Jingdong Medical District, Chinese PLA General Hospital, Beijing, China.
Chang LiuDepartment of General Internal Medicine, Jingdong Medical District, Chinese PLA General Hospital, Beijing, China.
Ruigang GeDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Wei YuDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Chuanbin XiDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Lingling MengDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Weiwei YanDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Zhongjian JuDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Lin MaDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China. malinpharm@sina.com.
Baolin QuDepartment of Radiation Oncology, the First Medical Center, Chinese PLA General Hospital, Beijing, China. qubl6212@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared deep inspiration breath-hold (DIBH) versus free-breathing (FB) techniques in postoperative radiotherapy for left-sided breast cancer. Dosimetric parameters for 94 patients were analyzed. DIBH significantly improved target conformity while reducing cardiac exposure, with mean heart dose decreasing by 2.631 Gy (EQD2). Significant dose reductions were also observed in bilateral lungs, esophagus, and spinal cord. A weak correlation was identified between left lung volume expansion and organ-at-risk dose reduction. Receiver operating characteristic analysis determined that a left lung volume increase of 807.1 cc predicted clinically meaningful cardiac protection. DIBH demonstrates effective organ sparing while only marginally compromising target coverage. Additionally, lung volume expansion could serve as a potential patient selection criterion.

Indexed as

Breath HoldingUnilateral Breast NeoplasmsFemaleHumansMiddle AgedOrgans at RiskRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedDeep inspiration breath-holdDosimetric parametersFree-breathingLeft-sided breast cancerRadiotherapy

Identifiers

PMID41760674
PMCPMC13009475

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.