Evidence map›Paper›PMID 41760579›Full record

Observational studyInternational wound journal2026

Wound Management and Surgery for Calcific Uremic Arteriolopathy (Calciphylaxis): A Retrospective Observational Cohort Study.

Scott J Moses, Matthew Supple, Houda Bouchouari, Rosalynn M Nazarian, Steven Chen, Madeline E DeWane, Sagar U Nigwekar, Maureen McCarthy, Sean Hickey, Jeremy Goverman

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International wound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Calciphylaxis in children: a case series and systematic review.Pediatric nephrology (Berlin, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Scott J MosesDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0005-9559-0270
Matthew SuppleDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Houda BouchouariDepartment of Medicine, Division of Nephrology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Rosalynn M NazarianPathology Service, Dermatopathology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Steven ChenDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Madeline E DeWaneDepartment of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Sagar U NigwekarDepartment of Medicine, Division of Nephrology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Maureen McCarthyDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Sean HickeyDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jeremy GovermanDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound care in calciphylaxis remains poorly defined without evidence-based consensus on timing and technique of surgical intervention. We demonstrate that surgical debridement and subsequent wound closure are safe and effective in calciphylaxis and describe a systematic multidisciplinary approach to intervention. We retrospectively reviewed a cohort of patients with calciphylaxis at our institution. Those who underwent surgical debridement and wound closure were analysed with emphasis on wound healing, progression to amputation and mortality. Sixty-two patients with calciphylaxis underwent surgical debridement. Twenty patients had wound closure by skin grafting, five were excised with primary wound closure, and 37 were debrided and allowed to heal by secondary intention. There were excellent rates of healing in all groups, and no patients demonstrated wound progression or new lesions following operative intervention. Surgical debridement and wound closure are safe and effective in treating wounds related to calciphylaxis.

Indexed as

CalciphylaxisDebridementSkin TransplantationWound HealingAdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomecalciphylaxisdebridementhealingskin‐graftingwoundwound closure

Identifiers

PMID41760579
PMCPMC12948643

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.