Evidence map›Paper›PMID 41760336›Full record

ArticleIn vivo (Athens, Greece)

Biologic Functionalization of a Biphasic Bone Substitute With Enamel Matrix Derivative Modulates Early Foreign Body Reaction in a Subcutaneous Mouse Model.

Tadas Korzinskas, Sanja Stojanovic, Stevo Najman, Ole Jung, Mike Barbeck

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tadas KorzinskasDepartment of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Institute for Dental and Craniofacial Sciences, Benjamin Franklin Charité Campus, Berlin, Germany.
Sanja StojanovicScientific Research Center for Biomedicine, Department for Cell and Tissue Engineering, Faculty of Medicine, University of Niš, Niš, Serbia.
Stevo NajmanScientific Research Center for Biomedicine, Department for Cell and Tissue Engineering, Faculty of Medicine, University of Niš, Niš, Serbia.
Ole JungClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.
Mike BarbeckClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany mike.barbeck@med.uni-rostock.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimBiologic enhancement of bone grafts with enamel matrix derivative (EMD) may improve regenerative outcomes by modulating the host tissue response. This study evaluated the in vivo tissue reaction to a biphasic bone substitute (Maxresorb MATERIALS AND

methodsForty BALB/c mice received subcutaneous implants of Maxresorb

resultsThe Maxresorb

conclusionThe combination of EMD and Maxresorb

Indexed as

Bone SubstitutesDental Enamel ProteinsForeign-Body ReactionAnimalsDisease Models, AnimalGiant CellsMacrophagesMiceMice, Inbred BALB CSubcutaneous TissueBone SubstitutesDental Enamel Proteinsenamel matrix proteinsbone tissue regenerationDIN EN ISO 10993-6Enamel matrix protein derivativemacrophagesmultinucleated giant cellstissue reaction

Identifiers

PMID41760336
PMCPMC12949921

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.