Evidence map›Paper›PMID 41760332›Full record

ArticleIn vivo (Athens, Greece)

Association Between AI-derived Thoracic Calcium Volume and Aortic Valve Calcification Quantified by Agatston Scoring.

Gonçalo G Almeida, Dana Belde, Mike Guldimann, Stephan Engelberger, André Euler, Fabienne Knöpfli, Rahel A Kubik-Huch, Michael Thali, Tilo Niemann

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Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Gonçalo G AlmeidaDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
Dana BeldeDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
Mike GuldimannDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
Stephan EngelbergerDepartment of Surgery, Section of Vascular Surgery, Kantonsspital Baden, Baden, Switzerland.
André EulerDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
Fabienne KnöpfliDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
Rahel A Kubik-HuchDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
Michael ThaliDepartment of Forensic Medicine Zurich, University of Zurich, Zurich, Switzerland.
Tilo NiemannDepartment of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland; tilo.niemann@ksb.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAortic valve calcification is a key determinant of aortic stenosis severity. Whether AI-derived thoracic aortic calcium volume reflects valvular calcification remains unclear. This study examined the association between aortic valve calcification quantified using Agatston, volume and mass scores, and total aortic calcium volume measured with an automated AI tool. PATIENTS AND

methodsThis retrospective single-center study included 32 patients undergoing computed tomography (CT) for transcatheter aortic valve implantation planning. Aortic valve calcification was quantified on noncontrast CT using Agatston, volume and mass scores. Total aortic calcium volume was derived from contrast-enhanced CT using the AI-Rad Companion Chest CT. Correlation analyses and simple linear regression assessed associations between aortic and valvular calcification metrics.

resultsMean total aortic calcium volume was 4.38 ml. Mean aortic valve Agatston score was 3307 units and mean valve calcium volume was 2727 mm

conclusionAI-derived thoracic aortic calcium volume did not correlate with aortic valve calcification. Valvular calcification appears to progress independently of thoracic aortic wall calcification. Automated aortic calcium measurements cannot substitute for direct quantification of aortic valve calcification in preprocedural assessment.

Indexed as

Aorta, ThoracicAortic ValveAortic Valve StenosisArtificial IntelligenceCalcinosisCalciumAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesSeverity of Illness IndexTomography, X-Ray ComputedCalciumaortic valve calcificationAortic valve stenosiscalcium scoringcomputed tomographytranscatheter aortic valve replacement

Identifiers

PMID41760332
PMCPMC12949879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.