ArticleIn vivo (Athens, Greece)
Density of Blood and Lymphatic Vessels in Stretch Marks: A Preliminary Study.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
backgroundAlthough stretch marks are not a medical condition, they are an esthetic defect and can have a negative impact on self-esteem. The causes of stretch marks are mainly hormonal factors, rapid weight gain, weight loss, pregnancy, and genetic factors. The aim of this study was to assess the expression level of markers of angiogenesis (CD31 MATERIALS AND
methodsThe material for the study consisted of 28 skin sections (14 skin samples with striae and 14 healthy skin samples) collected from Caucasian women during plastic surgery. Immunohistochemical reactions were performed using antibodies to CD31, CD34 and podoplanin, and were evaluated using light microscopy. The absolute number of vessels in the field of view was counted.
resultsImmunohistochemical reactions showed the presence of mature (CD31
conclusionThese preliminary data suggest that vascular remodeling in striae may involve the lymphatic compartment more than the blood microvasculature. Larger studies incorporating lesion stage, clinical correlates, and additional functional markers are warranted to clarify the contribution of (lymph)angiogenesis to striae pathogenesis and to inform aesthetic and cosmetology-oriented interventions.
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