Evidence map›Paper›PMID 41760309›Full record

ArticleIn vivo (Athens, Greece)

Density of Blood and Lymphatic Vessels in Stretch Marks: A Preliminary Study.

Aleksandra Piotrowska, Agnieszka Ciszek, Aleksandra Partyńska, Agnieszka Gomułkiewicz, Waldemar Andrzejewski, Andrzej Bieniek, Piotr Dzięgiel

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aleksandra PiotrowskaDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Wroclaw, Poland; aleksandra.piotrowska@umw.edu.pl.
Agnieszka CiszekDepartment of Human Biology and Cosmetology, Wroclaw University of Health and Sport Sciences, Wroclaw, Poland.
Aleksandra PartyńskaDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Wroclaw, Poland.
Agnieszka GomułkiewiczDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Wroclaw, Poland.
Waldemar AndrzejewskiDepartment of Physiotherapy, Wroclaw University of Health and Sport Sciences, Wroclaw, Poland.
Andrzej BieniekUniversity Centre of General Dermatology and Oncodermatology, Wroclaw Medical University, Wroclaw, Poland.
Piotr DzięgielDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Wroclaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough stretch marks are not a medical condition, they are an esthetic defect and can have a negative impact on self-esteem. The causes of stretch marks are mainly hormonal factors, rapid weight gain, weight loss, pregnancy, and genetic factors. The aim of this study was to assess the expression level of markers of angiogenesis (CD31 MATERIALS AND

methodsThe material for the study consisted of 28 skin sections (14 skin samples with striae and 14 healthy skin samples) collected from Caucasian women during plastic surgery. Immunohistochemical reactions were performed using antibodies to CD31, CD34 and podoplanin, and were evaluated using light microscopy. The absolute number of vessels in the field of view was counted.

resultsImmunohistochemical reactions showed the presence of mature (CD31

conclusionThese preliminary data suggest that vascular remodeling in striae may involve the lymphatic compartment more than the blood microvasculature. Larger studies incorporating lesion stage, clinical correlates, and additional functional markers are warranted to clarify the contribution of (lymph)angiogenesis to striae pathogenesis and to inform aesthetic and cosmetology-oriented interventions.

Indexed as

Blood VesselsLymphatic VesselsSkinStriae DistensaeAdultAngiogenesisAntigens, CD34BiomarkersFemaleHumansImmunohistochemistryLymphangiogenesisMembrane GlycoproteinsPlatelet Endothelial Cell Adhesion Molecule-1PodoplaninAntigens, CD34BiomarkersMembrane GlycoproteinsPDPN protein, humanPlatelet Endothelial Cell Adhesion Molecule-1PodoplaninangiogenesislymphangiogenesisStretch marks

Identifiers

PMID41760309
PMCPMC12949906

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.