Evidence map›Paper›PMID 41760302›Full record

ReviewIn vivo (Athens, Greece)

Appendiceal Tumors: A Narrative Review.

Alfredo Colombo, Vittorio Gebbia, Maria Rosaria Valerio

Abstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alfredo ColomboOncology Unit C.D.C. Macchiarella, Palermo, Italy; alfredocolombo63@gmail.com.
Vittorio GebbiaChair of Medical Oncology, Kore University of Enna, Enna, Italy.
Maria Rosaria ValerioOncology Unit, Chair of Medical Oncology, Policlinico, University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Appendiceal tumors (ATs) are classified by the World Health Organization's (WHO) 5th edition of their categorization of digestive system tumors into four subtypes: mucinous neoplasms, adenocarcinomas, serrated lesions, polyps, and neuroendocrine neoplasms (NENs). Due to their rarity and the lack of data from randomized controlled studies, ATs can be challenging to differentiate in medical practice. Specimens obtained during appendectomies for clinically acute appendicitis typically contain ATs. Most ATs in the European population affect women over 50 years. Neuroendocrine tumors (NETs) are the most common histological type, comprising 54.6%, followed by cystic, mucinous, and serous neoplasms (26.7%) and adenocarcinoma not otherwise defined (NOS) (18.6%). Most findings of ATs on pathologic investigation are benign lesions or small NENs that do not require additional treatment. The development of pseudomyxoma peritonei (PMP), a complicated situation of peritoneal carcinomatosis, may result from the presence of appendiceal mucinous neoplasm (AMN). Over the past few decades, multimodal treatment for abdominal cancers has advanced; however, ATs' clinical diagnosis and management are still debated. This review aims to outline the diagnostic options, molecular-based diagnosis, staging, treatment, and prognostic markers related to ATs.

Indexed as

Appendiceal NeoplasmsBiomarkers, TumorFemaleHumansNeoplasm StagingNeuroendocrine TumorsPrognosisBiomarkers, Tumorappendiceal cancerappendiceal surgeryChemotherapygastrointestinal stromal tumorsreviewtargeted therapy

Identifiers

PMID41760302
PMCPMC12949922

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.