Evidence map›Paper›PMID 41760212›Full record

ArticleSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2026

[Hemodynamic study of muscle perfusion in amputees].

Taoping Bai, Jiezhong Xue, Zhongyou Li, Xiao Li, Fei Yan, Wentao Jiang

Abstract readEnglish Abstract
In one paragraph

Article in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Taoping BaiDepartment of Mechanics Science and Engineering, Sichuan University, Sichuan Provincial Key Laboratory of Biomechanical Engineering, Chengdu 610065, P. R. China.
Jiezhong XueDepartment of Mechanics Science and Engineering, Sichuan University, Sichuan Provincial Key Laboratory of Biomechanical Engineering, Chengdu 610065, P. R. China.
Zhongyou LiDepartment of Mechanics Science and Engineering, Sichuan University, Sichuan Provincial Key Laboratory of Biomechanical Engineering, Chengdu 610065, P. R. China.
Xiao LiDepartment of Mechanics Science and Engineering, Sichuan University, Sichuan Provincial Key Laboratory of Biomechanical Engineering, Chengdu 610065, P. R. China.
Fei YanDepartment of Mechanics Science and Engineering, Sichuan University, Sichuan Provincial Key Laboratory of Biomechanical Engineering, Chengdu 610065, P. R. China.
Wentao JiangDepartment of Mechanics Science and Engineering, Sichuan University, Sichuan Provincial Key Laboratory of Biomechanical Engineering, Chengdu 610065, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To provide a reference for determining the hemodynamic environment of blood vessels and the nutrient supply of residual limbs, as well as for rehabilitation treatments aimed at reducing muscle atrophy after amputation, this study employed contrast-enhanced computed tomography technology to obtain angiographic images of the vascular system in residual limbs. A vascular model was established through three-dimensional reconstruction and mesh generation, followed by hemodynamic analysis using the finite element method. Based on the blood flow velocities in the femoral artery-0.09 m/s at rest, 0.23 m/s during exercise, and 0.32 m/s during steady-state exercise-the inlet velocities of the residual limb arteries were determined. Calculations yielded the inlet flow velocity, blood flow rate, and blood supply volume. As the inlet velocity increased, the mass flow rates in the superficial femoral artery and deep femoral artery showed the most significant increases, reaching 2.50E-3 kg/s and 2.67E-3 kg/s, respectively. In contrast, the blood flow in the lateral and medial femoral circumflex arteries did not exhibit significant changes. Increasing the inflow velocity did not significantly alter the minimal wall shear stress in the vessels. However, the maximum wall pressure in each vessel rose significantly with increased mass flow rate. Excessively high wall pressure may trigger atherosclerosis, particularly in higher-positioned vessels such as the superficial femoral artery. In addition, due to differences in blood supply, muscles experienced varying degrees of atrophy. Specific treatments for atherosclerosis should be considered during limb rehabilitation. Future research might explore combining rehabilitation training with other methods to promote localized muscle blood supply.

Indexed as

Amputation StumpsAmputation, SurgicalHemodynamicsMuscle, SkeletalBlood Flow VelocityFemoral ArteryFinite Element AnalysisHumansRegional Blood FlowFinite element analysisHemodynamics of the residual limbMuscle atrophyRehabilitation intervention

Identifiers

PMID41760212
PMCPMC12948532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.