Evidence map›Paper›PMID 41760210›Full record

ArticleSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2026

[Numerical simulation study on the influence of free edge configuration on the performance of polymeric heart valves].

Yang Xiao, Jianjun Hu, Qianwen Hou, Yijun Guo, Enhui Han, Jianye Zhou

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yang XiaoCollege of Architectural Engineering and Mechanics, Yanshan University, Qinhuangdao, Hebei 066004, P. R. China.
Jianjun HuCollege of Architectural Engineering and Mechanics, Yanshan University, Qinhuangdao, Hebei 066004, P. R. China.
Qianwen HouState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fu Wai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, P. R. China.
Yijun GuoSchool of Mechanical Engineering, Yanshan University, Qinhuangdao, Hebei 066004, P. R. China.
Enhui HanCollege of Architectural Engineering and Mechanics, Yanshan University, Qinhuangdao, Hebei 066004, P. R. China.
Jianye ZhouState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fu Wai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate the effects of curved and straight free edges on the hemodynamic performance and mechanical properties of polymeric heart valves. Two aortic valve models with different free-edge configurations were established, and valve motion throughout the entire cardiac cycle was simulated using a two-way fluid-structure interaction (FSI) method. Hemodynamic parameters and stress distribution characteristics were compared and analyzed. The results revealed that the curved free edge valve exhibited a significantly faster opening response than the straight free edge valve, with an approximately 13% increase in the effective orifice area (EOA) and an approximately 27% reduction in regurgitant volume. However, after valve closure, the curved free-edge model demonstrated higher stress levels across all critical regions. The free-edge configuration did not significantly alter the vortical structure within the aortic flow field; both models exhibited a flow pattern characterized by a combination of sinus vortices and wall-mounted spindle-shaped vortices. The findings indicate that a curved free edge can improve valve opening efficiency and regurgitation control, but may exacerbate stress concentration during closure, potentially increasing the risk of fatigue damage to the valve.

Indexed as

Aortic ValveHeart Valve ProsthesisHemodynamicsModels, CardiovascularComputer SimulationHumansPolymersProsthesis DesignStress, MechanicalPolymersAortic valveFluid-structure interactionFree edge configurationsHemodynamics

Identifiers

PMID41760210
PMCPMC12948531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.