Evidence map›Paper›PMID 41760154›Full record

Trial reportBMJ open2026

Prosthetist screening for comorbidity during routine care visits: a randomised controlled clinical trial evaluating benefits, acceptability and feasibility.

Jaclyn M Sions, Samantha J Stauffer, John R Horne, Ryan T Pohlig

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05410548 (Can Comorbidity Screening and Referral by Prosthetists Enhance Post-Amputation Care?), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05410548 nacompletednot on this map

Can Comorbidity Screening and Referral by Prosthetists Enhance Post-Amputation Care?

TypeinterventionalSponsorUniversity of DelawareRan2022 to 2023Enrolled70ConditionsLimb Ischemia, Low Back Pain, Depression, NeuropathyArmsStandard-of-Care, Clinical Screening
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jaclyn M SionsDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA megsions@udel.edu.ORCID http://orcid.org/0000-0002-8151-1341
Samantha J StaufferDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.ORCID http://orcid.org/0000-0002-3050-1071
John R HorneIndependence Prosthetics-Orthotics, Inc, Newark, Delaware, USA.
Ryan T PohligBiostatistics Core, University of Delaware, Newark, Delaware, USA.

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI SIONS, JACLYN MEGAN · 2016 to 2025
$23.3M
NIGMS NIH HHS P20 GM113125
6 · The paper itself

Abstract

objectivesComorbidity among adults with lower-limb amputation exceeds that in the general population and contributes to poor outcomes. The primary objectives of this clinical trial were to explore benefits, acceptability and feasibility of comorbidity screening by prosthetists during routine follow-up visits. Our primary hypothesis was that when compared with standard-of-care (SOC) follow-up visits, standard-of-care + comorbidity screening (SOC+) would result in greater patient satisfaction and reduced prosthetic care minutes.

designRandomised controlled clinical trial with mixed-methods approach. SETTINGS: Prosthetic clinical practices.

participants70 adults with unilateral lower-limb amputation.

interventionsParticipants were randomly assigned to receive SOC or SOC+, which included assessment for depressive symptoms, suicidal ideation, moderate-to-high risk low back pain, lack of pedal pulses suggestive of peripheral arterial disease and lack of protective sensation suggestive of peripheral neuropathy. Screening results were reviewed with participants and faxed to primary care with telephone follow-ups when indicated. Prosthetists participated in a focus group. Healthcare utilisation over the subsequent 3 months was tracked. PRIMARY AND SECONDARY OUTCOME MEASURES: Patient satisfaction surveys and care utilisation.

resultsFew adverse events and protocol deviations occurred; intervention fidelity was >95%. There were no significant between-group differences in overall patient satisfaction, prosthetic care utilisation over the subsequent 3 months, nor initial prosthetic care visit length (p>0.050). Item-by-item analysis found participants rated prosthetist responsiveness to concerns higher with SOC+ (p=0.046, r=0.251). Prosthetists identified benefits from screening. Screening prompted positive healthcare seeking behaviours in this vulnerable population.

conclusionsComorbidity screening by prosthetists appears feasible and acceptable. TRIAL REGISTRATION NUMBER: NCT05410548.

Indexed as

Amputation, SurgicalMass ScreeningAdultAgedComorbidityDepressionFeasibility StudiesFemaleHumansLow Back PainMaleMiddle AgedPatient Acceptance of Health CarePatient SatisfactionSuicidal IdeationBack painClinical TrialDepression & mood disordersDiabetic neuropathy

Identifiers

PMID41760154
PMCPMC12959007

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.