Evidence map›Paper›PMID 41759552›Full record

ArticleMicrobiology spectrum2026

Antifungal potential of naphthoquinone derivatives: screening of shikonin-based compounds and mechanistic insights into 5,8-dihydroxy-1,4-naphthoquinone against

Qingqing Chen, Minkai Yang, Xiaohui Lai, Jiabao Hu, Aliya Fazal, Yahan Zhang, Xiaoran Lv, Jiaxuan Xiao, Zheng Fan, Zichen Pan and 8 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Qingqing Chen *State Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Minkai Yang *State Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Xiaohui Lai *State Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Jiabao Hu *State Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Aliya FazalState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Yahan ZhangState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Xiaoran LvState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Jiaxuan XiaoState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Zheng FanState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Zichen PanState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Tongming YinCo-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, Jiangsu, China.
Shucun SunState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Guihua LuState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Jinliang QiState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Hongyan LinState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Zhongling WenState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Yonghua YangState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.ORCID 0000-0002-8647-1158
Hongwei HanState Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.ORCID 0009-0009-3705-6167

Funding

National Natural Science Foundation of China U1903201, 21702100, 21907051Natural Science Foundation of Jiangsu Province BK20191254Program for Changjiang Scholars and Innovative Research Team in University IRT_14R27
6 · The paper itself

Abstract

Invasive fungal infections (IFIs), predominantly caused by

Indexed as

Antifungal AgentsCandida albicansCandidiasisNaphthoquinonesAnimalsBiofilmsDisease Models, AnimalFemaleHumansHyphaeMiceMicrobial Sensitivity TestsOxidative StressAntifungal AgentsNaphthoquinonesshikoninantifungalbiofilm disruptionCandida albicansglycolysis inhibitionnaphthoquinone derivativesoxidative stress

Identifiers

PMID41759552
PMCPMC13055237

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.