Evidence map›Paper›PMID 41759465›Full record

ArticlePoultry science2026

A national study confirms a low occurrence of antimicrobial resistance amongst Escherichia coli isolates from the caecae of Australian meat chickens.

Rebecca Abraham, David Jordan, Marin Milotic, David J Hampson, Anthony Pavic, Sue Sharpe, Kylie Hewson, Shewli Mukerji, Kittitat Lugsomya, Sam Abraham

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebecca AbrahamAntimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Western Australia 6150, Australia; School of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia.
David JordanAntimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Western Australia 6150, Australia; School of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia.
Marin MiloticAntimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Western Australia 6150, Australia; School of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia.
David J HampsonSchool of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia; School of Veterinary Medicine, Murdoch University, Perth, Western Australia 6150, Australia.
Anthony PavicBirling Laboratories, Marsden Park, NSW 2765, Australia.
Sue SharpeBirling Laboratories, Marsden Park, NSW 2765, Australia.
Kylie HewsonAustralian Chicken Meat Federation, North Sydney, NSW, North Sydney 2059, Australia; Animal Health and Environment, Minimising Antimicrobial Resistance Mission Health and Biosecurity, CSIRO, ACT 260, Australia.
Shewli MukerjiAntimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Western Australia 6150, Australia; School of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia.
Kittitat LugsomyaAntimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Western Australia 6150, Australia; School of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia; Faculty of Veterinary Medicine, Mahanakorn University of Technology, Bangkok 10530, Thailand.
Sam AbrahamAntimicrobial Resistance and Infectious Diseases Laboratory, Harry Butler Institute, Murdoch University, Perth, Western Australia 6150, Australia; School of Medical, Molecular and Forensic Sciences, Murdoch University, Perth, Western Australia 6150, Australia. Electronic address: s.abraham@murdoch.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In meat chickens, Escherichia coli has been widely used as an indicator of overall carriage of antimicrobial resistance (AMR), with low levels of AMR found in Australia's 2016 national survey. This follow-up survey applied a high-throughput robotic antimicrobial-susceptibility platform to increase the probability of detecting rare but clinically significant forms of resistance, obtain higher-resolution prevalence estimates and assess possible temporal changes in amounts and types of resistance. Pooled caecal samples were collected at slaughter from 20 processing plants covering > 90% of Australian national chicken meat production. E. coli colonies were tested by broth micro-dilution against 14 antimicrobials and whole-genome sequencing was performed on all isolates that were clinically resistant to ciprofloxacin. Among 2,950 E. coli isolates, 56.8% were wild-type to every drug and all were susceptible to colistin and amikacin. Non-wild-type (NWT) rates were highest for tetracycline (23.3%, 95% CI 21.7-24.8%) and ampicillin (11.7%, 95% CI 10.5-12.9%); NWT prevalence for ciprofloxacin was 3.3% (2.6-4.0%, 95% CI 2.6-4.0%) but only 1.1% were resistant at the clinical breakpoint. Multi-class resistance was rare (2.9%). The genomes of 32 ciprofloxacin-resistant isolates were sequenced: 25 (78%) carried canonical gyrA/parC mutations and mainly clustered in two lineages, ST354 (n = 16) and ST752 (n = 9). When compared to contemporary European Union surveillance data, E. coli colonizing Australian meat-chickens continue to exhibit relatively low levels of resistance to first line and critically important antimicrobials. The stable but detectable presence of fluoroquinolone-resistant ST354 and ST752 underscores the need for regular large-scale, genomics-enabled surveillance.

Indexed as

Anti-Bacterial AgentsCecumChickensDrug Resistance, BacterialDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsPoultry DiseasesAnimalsAustraliaMicrobial Sensitivity TestsPrevalenceWhole Genome SequencingAnti-Bacterial AgentsAMRAustraliaEscherichia coliMeat-chickensSurvey

Identifiers

PMID41759465
PMCPMC12955623

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.